MYDGF


Summary: The protein encoded by this gene was previously thought to support proliferation of lymphoid cells and was considered an interleukin. However, this activity has not been reproducible and the function of this protein is currently unknown. [provided by RefSeq, Jul 2008].

NameOMIM IDEnsembl IDHGNC IDPHARMGKB IDMap Location
myeloid derived growth factorMIM:606746Ensembl:ENSG00000074842HGNC:HGNC:16948PA2982719p13.3

Gene Categories:

DRUGGABLE GENOME

GO terms in MYDGF


Term TypeEvidence TypeGO Term IDGO Des.
MFIPIGO:0005515protein binding
CCIDAGO:0005615extracellular space
CCTASGO:0005788endoplasmic reticulum lumen
CCIEAGO:0005793endoplasmic reticulum-Golgi intermediate compartment
BPIEAGO:0001525angiogenesis
BPISSGO:0001934positive regulation of protein phosphorylation
BPIDAGO:0001938positive regulation of endothelial cell proliferation
BPIEAGO:0006915apoptotic process
BPISSGO:0014068positive regulation of phosphatidylinositol 3-kinase signaling
BPTASGO:0036498IRE1-mediated unfolded protein response
BPISSGO:0043066negative regulation of apoptotic process
BPISSGO:0043410positive regulation of MAPK cascade
BPIDAGO:0045766positive regulation of angiogenesis
BPISSGO:0045944positive regulation of transcription by RNA polymerase II
BPISSGO:0051897positive regulation of protein kinase B signaling

Gene expression in normal tissue: MYDGF

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in MYDGF


DatabasePathway IDPathway Des.
wikipathwaysWP3472XBP1(S) activates chaperone genes
reactomeR-HSA-381038XBP1(S) activates chaperone genes
reactomeR-HSA-381070IRE1alpha activates chaperones
reactomeR-HSA-381119Unfolded Protein Response (UPR)
reactomeR-HSA-392499Metabolism of proteins

Gene-Drug: Aster Plot


Drug IDDrug NameModel Num.
iGMDRD353PD03259012

Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in MYDGF

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