SLC2A9
Summary: This gene encodes a member of the SLC2A facilitative glucose transporter family. Members of this family play a significant role in maintaining glucose homeostasis. The encoded protein may play a role in the development and survival of chondrocytes in cartilage matrices. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008].
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Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
OMIM IDMIM:606142 Ensembl IDEnsembl:ENSG00000109667 HGNC IDHGNC:HGNC:13446 PHARMGKB IDPA37771 Map Location4p16.1 | |||||
GO terms in SLC2A9
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Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| MF | NAS | GO:0005351 | carbohydrate:proton symporter activity |
| MF | IEA | GO:0005355 | glucose transmembrane transporter activity |
| MF | IDA | GO:0015143 | urate transmembrane transporter activity |
| MF | TAS | GO:0022857 | transmembrane transporter activity |
| BP | TAS | GO:0008645 | hexose transmembrane transport |
| BP | IEA | GO:0015747 | urate transport |
Gene expression in normal tissue: SLC2A9
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in SLC2A9
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Database | Pathway ID | Pathway Des. |
|---|---|---|
| wikipathways | WP2882 | Nuclear Receptors Meta-Pathway |
| wikipathways | WP2884 | NRF2 pathway |
| pharmgkb | PA166114721 | Uricosurics Pathway, Pharmacodynamics |
| reactome | R-HSA-1643685 | Disease |
| reactome | R-HSA-189200 | Cellular hexose transport |
| reactome | R-HSA-382551 | Transport of small molecules |
Gene-Drug: Aster Plot
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Drug ID | Drug Name | Model Num. |
|---|---|---|
| iGMDRD353 | PD0325901 | 1 |
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Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in SLC2A9
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Model | Level | Reference ID | Tissue | Cancer | Drug | Clinical Response | Source | |
|---|---|---|---|---|---|---|---|---|
| No matching records found | ||||||||
CLASSFICATION
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