KCNK12
Summary: This gene encodes one of the members of the superfamily of potassium channel proteins containing two pore-forming P domains. The product of this gene has not been shown to be a functional channel, however, it may require other non-pore-forming proteins for activity. [provided by RefSeq, Jul 2008].
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| potassium two pore domain channel subfamily K member 12 | MIM:607366 | Ensembl:ENSG00000184261 | HGNC:HGNC:6274 | PA30054 | 2p16.3 |
GO terms in KCNK12
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| MF | IEA | GO:0005244 | voltage-gated ion channel activity |
| MF | IBA | GO:0022841 | potassium ion leak channel activity |
| CC | IBA | GO:0005887 | integral component of plasma membrane |
| BP | IBA | GO:0030322 | stabilization of membrane potential |
| BP | IEA | GO:0034765 | regulation of ion transmembrane transport |
| BP | IBA | GO:0071805 | potassium ion transmembrane transport |
Gene expression in normal tissue: KCNK12
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in KCNK12
| Database | Pathway ID | Pathway Des. |
|---|---|---|
| reactome | R-HSA-397014 | Muscle contraction |
| reactome | R-HSA-5576886 | Phase 4 - resting membrane potential |
| reactome | R-HSA-5576891 | Cardiac conduction |
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in KCNK12
CLASSFICATION
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