KCNK12


Summary: This gene encodes one of the members of the superfamily of potassium channel proteins containing two pore-forming P domains. The product of this gene has not been shown to be a functional channel, however, it may require other non-pore-forming proteins for activity. [provided by RefSeq, Jul 2008].

NameOMIM IDEnsembl IDHGNC IDPHARMGKB IDMap Location
potassium two pore domain channel subfamily K member 12MIM:607366Ensembl:ENSG00000184261HGNC:HGNC:6274PA300542p16.3

GO terms in KCNK12


Term TypeEvidence TypeGO Term IDGO Des.
MFIEAGO:0005244voltage-gated ion channel activity
MFIBAGO:0022841potassium ion leak channel activity
CCIBAGO:0005887integral component of plasma membrane
BPIBAGO:0030322stabilization of membrane potential
BPIEAGO:0034765regulation of ion transmembrane transport
BPIBAGO:0071805potassium ion transmembrane transport

Gene expression in normal tissue: KCNK12

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in KCNK12


DatabasePathway IDPathway Des.
reactomeR-HSA-397014Muscle contraction
reactomeR-HSA-5576886Phase 4 - resting membrane potential
reactomeR-HSA-5576891Cardiac conduction

Gene-Drug: Aster Plot


Drug IDDrug NameModel Num.
iGMDRD353PD03259012

Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in KCNK12

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