GRIPAP1
Summary: This gene encodes a guanine nucleotide exchange factor for the Ras family of small G proteins (RasGEF). The encoded protein interacts in a complex with glutamate receptor interacting protein 1 (GRIP1) and plays a role in the regulation of AMPA receptor function. [provided by RefSeq, Aug 2013].
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Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
OMIM IDMIM:300408 Ensembl IDEnsembl:ENSG00000068400 HGNC IDHGNC:HGNC:18706 PHARMGKB IDPA38650 Map LocationXp11.23 | |||||
GO terms in GRIPAP1
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Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| MF | ND | GO:0003674 | molecular_function |
| MF | IPI | GO:0005515 | protein binding |
| BP | ND | GO:0008150 | biological_process |
| BP | IEA | GO:0098887 | neurotransmitter receptor transport, endosome to postsynaptic membrane |
| BP | IEA | GO:1905244 | regulation of modification of synaptic structure |
| CC | IDA | GO:0005654 | nucleoplasm |
Gene expression in normal tissue: GRIPAP1
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in GRIPAP1
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Database | Pathway ID | Pathway Des. |
|---|---|---|
| No matching records found | ||
Gene-Drug: Aster Plot
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Drug ID | Drug Name | Model Num. |
|---|---|---|
| iGMDRD353 | PD0325901 | 1 |
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Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in GRIPAP1
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Model | Level | Reference ID | Tissue | Cancer | Drug | Clinical Response | Source | |
|---|---|---|---|---|---|---|---|---|
| No matching records found | ||||||||
CLASSFICATION
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