CELF4
Summary: Members of the CELF/BRUNOL protein family contain two N-terminal RNA recognition motif (RRM) domains, one C-terminal RRM domain, and a divergent segment of 160-230 aa between the second and third RRM domains. Members of this protein family regulate pre-mRNA alternative splicing and may also be involved in mRNA editing, and translation. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
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Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
---|---|---|---|---|---|
OMIM IDMIM:612679 Ensembl IDEnsembl:ENSG00000101489 HGNC IDHGNC:HGNC:14015 PHARMGKB IDPA25428 Map Location18q12.2 |
GO terms in CELF4
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Term Type | Evidence Type | GO Term ID | GO Des. |
---|---|---|---|
CC | IBA | GO:0005634 | nucleus |
CC | IDA | GO:0005634 | nucleus |
CC | IBA | GO:0005737 | cytoplasm |
CC | IEA | GO:0005737 | cytoplasm |
BP | IDA | GO:0000380 | alternative mRNA splicing, via spliceosome |
BP | IBA | GO:0000381 | regulation of alternative mRNA splicing, via spliceosome |
Gene expression in normal tissue: CELF4
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in CELF4
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Database | Pathway ID | Pathway Des. |
---|---|---|
wikipathways | WP411 | mRNA Processing |
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Gene-Drug: Aster Plot
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Drug ID | Drug Name | Model Num. |
---|---|---|
iGMDRD309 | 17AAG | 1 |
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Gene in drug-gene network: Network Plot

Gene-drug targets distribution
Gene Structure: PDB
Models in CELF4
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Model | Level | Reference ID | Tissue | Cancer | Drug | Clinical Response | Source | |
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No matching records found |