ANO2
Summary: ANO2 belongs to a family of calcium-activated chloride channels (CaCCs) (reviewed by Hartzell et al., 2009 [PubMed 19015192]).[supplied by OMIM, Jan 2011].
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| anoctamin 2 | MIM:610109 | Ensembl:ENSG00000047617 | HGNC:HGNC:1183 | PA25504 | 12p13.31 |
GO terms in ANO2
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| MF | IDA | GO:0005229 | intracellular calcium activated chloride channel activity |
| MF | TAS | GO:0005229 | intracellular calcium activated chloride channel activity |
| MF | IEA | GO:0042803 | protein homodimerization activity |
| MF | IEA | GO:0046982 | protein heterodimerization activity |
| BP | TAS | GO:0034220 | ion transmembrane transport |
| BP | IEA | GO:1902476 | chloride transmembrane transport |
| CC | IDA | GO:0005654 | nucleoplasm |
| CC | IDA | GO:0005886 | plasma membrane |
| CC | ISS | GO:0005886 | plasma membrane |
| CC | TAS | GO:0005886 | plasma membrane |
| CC | IEA | GO:0034707 | chloride channel complex |
| CC | IEA | GO:0097730 | non-motile cilium |
Gene expression in normal tissue: ANO2
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in ANO2
| Database | Pathway ID | Pathway Des. |
|---|---|---|
| reactome | R-HSA-2672351 | Stimuli-sensing channels |
| reactome | R-HSA-382551 | Transport of small molecules |
| reactome | R-HSA-983712 | Ion channel transport |
| kegg | hsa04740 | Olfactory transduction - Homo sapiens (human) |
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in ANO2
CLASSFICATION
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