ADGRG6


Summary: This gene, which is upregulated in human umbilical vein endothelial cells, encodes a G protein-coupled receptor. Variations in this gene can affect a person's stature. Multiple transcript variants encoding different proteins have been found for this gene. [provided by RefSeq, Mar 2009].

NameOMIM IDEnsembl IDHGNC IDPHARMGKB IDMap Location
adhesion G protein-coupled receptor G6MIM:612243Ensembl:ENSG00000112414HGNC:HGNC:13841PA1348783286q24.2

GO terms in ADGRG6


Term TypeEvidence TypeGO Term IDGO Des.
MFIBAGO:0001965G-protein alpha-subunit binding
MFIBAGO:0004930G-protein coupled receptor activity
MFIMPGO:0004930G-protein coupled receptor activity
MFISSGO:0004930G-protein coupled receptor activity
MFISSGO:0005518collagen binding
MFIBAGO:0043236laminin binding
MFISSGO:0043236laminin binding
MFISSGO:0050840extracellular matrix binding
CCIEAGO:0005622intracellular
CCIDAGO:0005886plasma membrane
CCIBAGO:0005887integral component of plasma membrane
CCIEAGO:0016021integral component of membrane
BPIEAGO:0007005mitochondrion organization
BPISSGO:0007166cell surface receptor signaling pathway
BPISSGO:0007186G-protein coupled receptor signaling pathway
BPIEAGO:0007189adenylate cyclase-activating G-protein coupled receptor signaling pathway
BPIMPGO:0014037Schwann cell differentiation
BPIMPGO:0019933cAMP-mediated signaling
BPISSGO:0019933cAMP-mediated signaling
BPIBAGO:0022011myelination in peripheral nervous system
BPISSGO:0022011myelination in peripheral nervous system
BPIMPGO:0042552myelination
BPIBAGO:0060347heart trabecula formation
BPIEAGO:0060347heart trabecula formation

Gene expression in normal tissue: ADGRG6

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in ADGRG6


DatabasePathway IDPathway Des.

Gene-Drug: Aster Plot


Drug IDDrug NameModel Num.
iGMDRD353PD03259011

Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in ADGRG6

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