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DSCAML1

Summary: The protein encoded by this gene is a member of the Ig superfamily of cell adhesion molecules and is involved in neuronal differentiation. The encoded membrane-bound protein localizes to the cell surface, where it forms aggregates that repel neuronal processes of the same cell type. [provided by RefSeq, Sep 2016].

Name	OMIM ID	Ensembl ID	HGNC ID	PHARMGKB ID	Map Location
DS cell adhesion molecule like 1	MIM:611782	Ensembl:ENSG00000177103	HGNC:HGNC:14656	PA38384	11q23.3

Gene Categories:

CELL SURFACE

GO terms in DSCAML1

Term Type	Evidence Type	GO Term ID	GO Des.
MF	IDA	GO:0042803	protein homodimerization activity
BP	NAS	GO:0001709	cell fate determination
BP	IDA	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
BP	NAS	GO:0007409	axonogenesis
BP	NAS	GO:0007417	central nervous system development
BP	IDA	GO:0007420	brain development
BP	NAS	GO:0009953	dorsal/ventral pattern formation
BP	IDA	GO:0048704	embryonic skeletal system morphogenesis
CC	HDA	GO:0005615	extracellular space
CC	TAS	GO:0005886	plasma membrane
CC	IDA	GO:0009986	cell surface
CC	IEA	GO:0016021	integral component of membrane
CC	IEA	GO:0030054	cell junction
CC	IEA	GO:0045202	synapse

Gene expression in normal tissue: DSCAML1

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Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in DSCAML1

Database	Pathway ID	Pathway Des.
reactome	R-HSA-1266738	Developmental Biology
reactome	R-HSA-373752	Netrin-1 signaling
reactome	R-HSA-376172	DSCAM interactions
reactome	R-HSA-422475	Axon guidance

Gene-Drug: Aster Plot

Drug ID	Drug Name	Model Num.
iGMDRD309	17AAG	2
iGMDRD68	Paclitaxel	1
iGMDRD353	PD0325901	1

Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in DSCAML1

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DATATYPES

CLASSFICATION

Disclaimer: iGMDR is intended for research purposes only. Its information cannot be used for emergencies or medical or professional advice.