SEMA6A
Summary: The transmembrane semaphorin SEMA6A is expressed in developing neural tissue and is required for proper development of the thalamocortical projection (Leighton et al., 2001 [PubMed 11242070]).[supplied by OMIM, Feb 2011].
Loading, please wait...
Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
Namesemaphorin 6A OMIM IDMIM:605885 Ensembl IDEnsembl:ENSG00000092421 HGNC IDHGNC:HGNC:10738 PHARMGKB IDPA35660 Map Location5q23.1 | |||||
GO terms in SEMA6A
Loading, please wait...
Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| MF | IPI | GO:0005515 | protein binding |
| MF | IBA | GO:0030215 | semaphorin receptor binding |
| MF | IBA | GO:0045499 | chemorepellent activity |
| BP | IBA | GO:0001755 | neural crest cell migration |
| BP | NAS | GO:0006915 | apoptotic process |
| BP | NAS | GO:0007010 | cytoskeleton organization |
Gene expression in normal tissue: SEMA6A
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in SEMA6A
Loading, please wait...
Database | Pathway ID | Pathway Des. |
|---|---|---|
| reactome | R-HSA-1266738 | Developmental Biology |
| reactome | R-HSA-373755 | Semaphorin interactions |
| reactome | R-HSA-416700 | Other semaphorin interactions |
| reactome | R-HSA-422475 | Axon guidance |
| wikipathways | WP2431 | Spinal Cord Injury |
| kegg | hsa04360 | Axon guidance - Homo sapiens (human) |
Showing 1 to 6 of 6 rows
Gene-Drug: Aster Plot
Loading, please wait...
Drug ID | Drug Name | Model Num. |
|---|---|---|
| iGMDRD309 | 17AAG | 1 |
Showing 1 to 1 of 1 rows
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in SEMA6A
Loading, please wait...
Model | Level | Reference ID | Tissue | Cancer | Drug | Clinical Response | Source | |
|---|---|---|---|---|---|---|---|---|
| No matching records found | ||||||||
CLASSFICATION
Copyright © 2018 Modellab | All Rights Reserved
Disclaimer: iGMDR is intended for research purposes only. Its information cannot be used for emergencies or medical or professional advice.