Summary: This gene belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. This family member contains 6 extracellular cadherin domains, a transmembrane domain and a cytoplasmic tail differing from those of the classical cadherins. The encoded protein is a cadherin-related neuronal receptor thought to function in the establishment of specific cell-cell connections in the brain. This gene plays a role in inhibiting cancer cell motility and cell migration. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2015].

protocadherin 10MIM:608286Ensembl:ENSG00000138650HGNC:HGNC:13404PA329954q28.3

GO terms in PCDH10

Term TypeEvidence TypeGO Term IDGO Des.
MFIEAGO:0005509calcium ion binding
BPIBAGO:0007155cell adhesion
BPIEAGO:0007156homophilic cell adhesion via plasma membrane adhesion molecules
BPIBAGO:0007267cell-cell signaling
CCIBAGO:0005887integral component of plasma membrane

Gene expression in normal tissue: PCDH10

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in PCDH10

DatabasePathway IDPathway Des.

Gene-Drug: Aster Plot

Drug IDDrug NameModel Num.

Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in PCDH10