EPS15L1
Summary:
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| epidermal growth factor receptor pathway substrate 15 like 1 | MIM:616826 | Ensembl:ENSG00000127527 | HGNC:HGNC:24634 | PA134906266 | 19p13.11 |
GO terms in EPS15L1
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| BP | IEA | GO:0006897 | endocytosis |
| BP | TAS | GO:0042059 | negative regulation of epidermal growth factor receptor signaling pathway |
| BP | TAS | GO:0061024 | membrane organization |
| CC | IEA | GO:0005634 | nucleus |
| CC | TAS | GO:0005829 | cytosol |
| CC | TAS | GO:0005886 | plasma membrane |
| CC | HDA | GO:0016020 | membrane |
| CC | IEA | GO:0030132 | clathrin coat of coated pit |
| MF | IEA | GO:0005509 | calcium ion binding |
| MF | IPI | GO:0005515 | protein binding |
| MF | HDA | GO:0045296 | cadherin binding |
Gene expression in normal tissue: EPS15L1
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in EPS15L1
| Database | Pathway ID | Pathway Des. |
|---|---|---|
| reactome | R-HSA-162582 | Signal Transduction |
| reactome | R-HSA-177929 | Signaling by EGFR |
| reactome | R-HSA-182971 | EGFR downregulation |
| reactome | R-HSA-199991 | Membrane Trafficking |
| reactome | R-HSA-5653656 | Vesicle-mediated transport |
| reactome | R-HSA-8856825 | Cargo recognition for clathrin-mediated endocytosis |
| reactome | R-HSA-8856828 | Clathrin-mediated endocytosis |
| reactome | R-HSA-9006934 | Signaling by Receptor Tyrosine Kinases |
| wikipathways | WP437 | EGF-EGFR Signaling Pathway |
| kegg | hsa04144 | Endocytosis - Homo sapiens (human) |
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in EPS15L1
CLASSFICATION
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