RRAGD

Summary: RRAGD is a monomeric guanine nucleotide-binding protein, or G protein. By binding GTP or GDP, small G proteins act as molecular switches in numerous cell processes and signaling pathways.[supplied by OMIM, Apr 2004].

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Name
OMIM ID
Ensembl ID
HGNC ID
PHARMGKB ID
Map Location
NameRas related GTP binding D
OMIM IDMIM:608268
Ensembl IDEnsembl:ENSG00000025039
HGNC IDHGNC:HGNC:19903
PHARMGKB IDPA134957148
Map Location6q15

Gene Categories:

TUMOR SUPPRESSOR

GO terms in RRAGD


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Term Type
Evidence Type
GO Term ID
GO Des.
BP TAS GO:0007050 cell cycle arrest
BP IBA GO:0009267 cellular response to starvation
BP IBA GO:0010506 regulation of autophagy
BP TAS GO:0016241 regulation of macroautophagy
BP IBA GO:0032008 positive regulation of TOR signaling
BP NAS GO:0032008 positive regulation of TOR signaling
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Gene expression in normal tissue: RRAGD

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in RRAGD


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Database
Pathway ID
Pathway Des.
reactome R-HSA-1257604 PIP3 activates AKT signaling
reactome R-HSA-162582 Signal Transduction
reactome R-HSA-1632852 Macroautophagy
reactome R-HSA-165159 mTOR signalling
reactome R-HSA-166208 mTORC1-mediated signalling
reactome R-HSA-212436 Generic Transcription Pathway
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Gene-Drug: Aster Plot


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Drug ID
Drug Name
Model Num.
iGMDRD309 17AAG 2
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Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in RRAGD

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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