ENPP5

Summary: This gene encodes a type-I transmembrane glycoprotein. Studies in rat suggest the encoded protein may play a role in neuronal cell communications. Alternatively spliced transcript variants have been described. [provided by RefSeq, Feb 2014].

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Name
OMIM ID
Ensembl ID
HGNC ID
PHARMGKB ID
Map Location
Nameectonucleotide pyrophosphatase/phosphodiesterase 5 (putative)
OMIM IDMIM:617001
Ensembl IDEnsembl:ENSG00000112796
HGNC IDHGNC:HGNC:13717
PHARMGKB IDPA27795
Map Location6p21.1

Gene Categories:

DRUGGABLE GENOME

GO terms in ENPP5


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Term Type
Evidence Type
GO Term ID
GO Des.
BP IEA GO:0007154 cell communication
BP IEA GO:0008152 metabolic process
CC IEA GO:0005576 extracellular region
CC IEA GO:0005886 plasma membrane
CC IEA GO:0016021 integral component of membrane
MF IEA GO:0016787 hydrolase activity
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Gene expression in normal tissue: ENPP5

Gene-model tissue-cancer distribution: Bubble Plot

undefinetissue: undefine cancer: undefined model num: 0undefinedtissue: undefined cancer: PANCAN model num: 3BREAStissue: BREAS cancer: BREAST model num: 0BREASTtissue: BREAST cancer: Breast Carcinoma model num: 1

Gene-drug pathway distribution

Metabolic pathways1Protein stability and degradation1

Pathways in ENPP5


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Database
Pathway ID
Pathway Des.
No matching records found

Gene-Drug: Aster Plot


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Drug ID
Drug Name
Model Num.
iGMDRD309 17AAG 2
iGMDRD68 Paclitaxel 2
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Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in ENPP5

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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