SENP2
Summary: SUMO1 (UBL1; MIM 601912) is a small ubiquitin-like protein that can be covalently conjugated to other proteins. SENP2 is one of a group of enzymes that process newly synthesized SUMO1 into the conjugatable form and catalyze the deconjugation of SUMO1-containing species.[supplied by OMIM, Apr 2004].
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Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
OMIM IDMIM:608261 Ensembl IDEnsembl:ENSG00000163904 HGNC IDHGNC:HGNC:23116 PHARMGKB IDPA134955185 Map Location3q27.2 | |||||
GO terms in SENP2
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Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| BP | IEA | GO:0001934 | positive regulation of protein phosphorylation |
| BP | IEA | GO:0007507 | heart development |
| BP | IEA | GO:0009950 | dorsal/ventral axis specification |
| BP | IEA | GO:0015031 | protein transport |
| BP | IEA | GO:0016055 | Wnt signaling pathway |
| BP | TAS | GO:0016925 | protein sumoylation |
Gene expression in normal tissue: SENP2
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in SENP2
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Database | Pathway ID | Pathway Des. |
|---|---|---|
| reactome | R-HSA-2990846 | SUMOylation |
| reactome | R-HSA-3065679 | SUMO is proteolytically processed |
| reactome | R-HSA-3215018 | Processing and activation of SUMO |
| reactome | R-HSA-392499 | Metabolism of proteins |
| reactome | R-HSA-597592 | Post-translational protein modification |
| wikipathways | WP428 | Wnt Signaling Pathway |
Gene-Drug: Aster Plot
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Drug ID | Drug Name | Model Num. |
|---|---|---|
| iGMDRD353 | PD0325901 | 1 |
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Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in SENP2
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Model | Level | Reference ID | Tissue | Cancer | Drug | Clinical Response | Source | |
|---|---|---|---|---|---|---|---|---|
| No matching records found | ||||||||
CLASSFICATION
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