RNASE2

Summary: The protein encoded by this gene is a non-secretory ribonuclease that belongs to the pancreatic ribonuclease family, a subset of the ribonuclease A superfamily. The protein antimicrobial activity against viruses. [provided by RefSeq, Oct 2014].

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Name
OMIM ID
Ensembl ID
HGNC ID
PHARMGKB ID
Map Location
Nameribonuclease A family member 2
OMIM IDMIM:131410
Ensembl IDEnsembl:ENSG00000169385
HGNC IDHGNC:HGNC:10045
PHARMGKB IDPA34413
Map Location14q11.2

Gene Categories:

DRUGGABLE GENOME

GO terms in RNASE2


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Term Type
Evidence Type
GO Term ID
GO Des.
MF IMP GO:0001530 lipopolysaccharide binding
MF IEA GO:0003676 nucleic acid binding
MF IBA GO:0004519 endonuclease activity
MF IEA GO:0004522 ribonuclease A activity
MF IBA GO:0004540 ribonuclease activity
MF IDA GO:0004540 ribonuclease activity
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Gene expression in normal tissue: RNASE2

Gene-model tissue-cancer distribution: Bubble Plot

undefinetissue: undefine cancer: undefined model num: 0undefinedtissue: undefined cancer: PANCAN model num: 1

Gene-drug pathway distribution

Pathways in RNASE2


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Database
Pathway ID
Pathway Des.
reactome R-HSA-168249 Innate Immune System
reactome R-HSA-168256 Immune System
reactome R-HSA-6798695 Neutrophil degranulation
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Gene-Drug: Aster Plot


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Drug ID
Drug Name
Model Num.
iGMDRD353 PD0325901 1
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Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in RNASE2

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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