RPL39


Summary: Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the S39E family of ribosomal proteins. It is located in the cytoplasm. In rat, the protein is the smallest, and one of the most basic, proteins of the ribosome. This gene is co-transcribed with the U69 small nucleolar RNA gene, which is located in its second intron. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008].

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Name
OMIM ID
Ensembl ID
HGNC ID
PHARMGKB ID
Map Location
OMIM IDMIM:300899
PHARMGKB IDPA34743
Map LocationXq24

GO terms in RPL39


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Term Type
Evidence Type
GO Term ID
GO Des.
CC IDA GO:0005615 extracellular space
CC TAS GO:0005829 cytosol
CC HDA GO:0022625 cytosolic large ribosomal subunit
CC IBA GO:0022625 cytosolic large ribosomal subunit
CC IDA GO:0022625 cytosolic large ribosomal subunit
CC TAS GO:0022625 cytosolic large ribosomal subunit
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Gene expression in normal tissue: RPL39

Gene-model tissue-cancer distribution: Bubble Plot

undefinetissue: undefine cancer: undefined model num: 0undefinedtissue: undefined cancer: PANCAN model num: 2

Gene-drug pathway distribution

Metabolic pathways1

Pathways in RPL39


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Database
Pathway ID
Pathway Des.
reactome R-HSA-1266738 Developmental Biology
reactome R-HSA-1430728 Metabolism
reactome R-HSA-156827 L13a-mediated translational silencing of Ceruloplasmin expression
reactome R-HSA-156842 Eukaryotic Translation Elongation
reactome R-HSA-156902 Peptide chain elongation
reactome R-HSA-1643685 Disease
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Gene-Drug: Aster Plot


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Drug ID
Drug Name
Model Num.
iGMDRD68 Paclitaxel 2
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Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in RPL39

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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