RPS9
Summary: Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S4P family of ribosomal proteins. It is located in the cytoplasm. Variable expression of this gene in colorectal cancers compared to adjacent normal tissues has been observed, although no correlation between the level of expression and the severity of the disease has been found. As is typical for genes encoding ribosomal proteins, multiple processed pseudogenes derived from this gene are dispersed through the genome. [provided by RefSeq, Jul 2008].
Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
OMIM IDMIM:603631 Ensembl IDEnsembl:ENSG00000170889 HGNC IDHGNC:HGNC:10442 PHARMGKB IDPA34857 Map Location19q13.42 | |||||
GO terms in RPS9
Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| MF | HDA | GO:0003723 | RNA binding |
| MF | IBA | GO:0003735 | structural constituent of ribosome |
| MF | IPI | GO:0005515 | protein binding |
| MF | IBA | GO:0019843 | rRNA binding |
| MF | IMP | GO:0045182 | translation regulator activity |
| BP | TAS | GO:0000184 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay |
Gene expression in normal tissue: RPS9
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in RPS9
Database | Pathway ID | Pathway Des. |
|---|---|---|
| reactome | R-HSA-1266738 | Developmental Biology |
| reactome | R-HSA-1430728 | Metabolism |
| reactome | R-HSA-156827 | L13a-mediated translational silencing of Ceruloplasmin expression |
| reactome | R-HSA-156842 | Eukaryotic Translation Elongation |
| reactome | R-HSA-156902 | Peptide chain elongation |
| reactome | R-HSA-1643685 | Disease |
Gene-Drug: Aster Plot
Drug ID | Drug Name | Model Num. |
|---|---|---|
| iGMDRD68 | Paclitaxel | 2 |
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in RPS9
Model | Level | Reference ID | Tissue | Cancer | Drug | Clinical Response | Source | |
|---|---|---|---|---|---|---|---|---|
| No matching records found | ||||||||
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