RPS20
Summary: Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S10P family of ribosomal proteins. It is located in the cytoplasm. This gene is co-transcribed with the small nucleolar RNA gene U54, which is located in its second intron. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. Two transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Apr 2009].
Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
OMIM IDMIM:603682 Ensembl IDEnsembl:ENSG00000008988 HGNC IDHGNC:HGNC:10405 PHARMGKB IDPA34807 Map Location8q12.1 | |||||
GO terms in RPS20
Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| MF | HDA | GO:0003723 | RNA binding |
| MF | HDA | GO:0003735 | structural constituent of ribosome |
| MF | IBA | GO:0003735 | structural constituent of ribosome |
| MF | NAS | GO:0003735 | structural constituent of ribosome |
| MF | IPI | GO:0005515 | protein binding |
| CC | TAS | GO:0005654 | nucleoplasm |
Gene expression in normal tissue: RPS20
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in RPS20
Database | Pathway ID | Pathway Des. |
|---|---|---|
| wikipathways | WP477 | Cytoplasmic Ribosomal Proteins |
| kegg | hsa03010 | Ribosome - Homo sapiens (human) |
| reactome | R-HSA-1266738 | Developmental Biology |
| reactome | R-HSA-1430728 | Metabolism |
| reactome | R-HSA-156827 | L13a-mediated translational silencing of Ceruloplasmin expression |
| reactome | R-HSA-156842 | Eukaryotic Translation Elongation |
Gene-Drug: Aster Plot
Drug ID | Drug Name | Model Num. |
|---|---|---|
| iGMDRD68 | Paclitaxel | 1 |
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in RPS20
Model | Level | Reference ID | Tissue | Cancer | Drug | Clinical Response | Source | |
|---|---|---|---|---|---|---|---|---|
| No matching records found | ||||||||
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