RTN2


Summary: This gene belongs to the family of reticulon encoding genes. Reticulons are necessary for proper generation of tubular endoplasmic reticulum and likely play a role in intracellular vesicular transport. Alternatively spliced transcript variants encoding different isoforms have been identified. Mutations at this locus have been associated with autosomal dominant spastic paraplegia-12. [provided by RefSeq, Apr 2012].

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Name
OMIM ID
Ensembl ID
HGNC ID
PHARMGKB ID
Map Location
OMIM IDMIM:603183
PHARMGKB IDPA34881
Map Location19q13.32

GO terms in RTN2


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Term Type
Evidence Type
GO Term ID
GO Des.
CC IDA GO:0005783 endoplasmic reticulum
CC IEA GO:0014802 terminal cisterna
CC NAS GO:0030176 integral component of endoplasmic reticulum membrane
CC IEA GO:0030315 T-tubule
BP IEA GO:0046324 regulation of glucose import
BP IEA GO:0065002 intracellular protein transmembrane transport
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Gene expression in normal tissue: RTN2

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in RTN2


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Database
Pathway ID
Pathway Des.
No matching records found

Gene-Drug: Aster Plot


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Drug ID
Drug Name
Model Num.
iGMDRD353 PD0325901 1
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Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in RTN2

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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