SALL2

Summary: This gene encodes a protein containing multiple zinc finger domains. The encoded protein functions in optical fissure closure during development of the eye in the embryo. Mutations in this gene are associated with ocular coloboma. [provided by RefSeq, Jul 2016].

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Name
OMIM ID
Ensembl ID
HGNC ID
PHARMGKB ID
Map Location
Namespalt like transcription factor 2
OMIM IDMIM:602219
Ensembl IDEnsembl:ENSG00000165821
HGNC IDHGNC:HGNC:10526
PHARMGKB IDPA34934
Map Location14q11.2

GO terms in SALL2


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Term Type
Evidence Type
GO Term ID
GO Des.
CC IBA GO:0005634 nucleus
CC IEA GO:0016581 NuRD complex
BP IBA GO:0000122 negative regulation of transcription by RNA polymerase II
BP IDA GO:0001654 eye development
BP IBA GO:0006355 regulation of transcription, DNA-templated
BP IBA GO:0007275 multicellular organism development
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Gene expression in normal tissue: SALL2

Gene-model tissue-cancer distribution: Bubble Plot

undefinetissue: undefine cancer: undefined model num: 0undefinedtissue: undefined cancer: PANCAN model num: 3

Gene-drug pathway distribution

Protein stability and degradation1ERK MAPK signaling1

Pathways in SALL2


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Database
Pathway ID
Pathway Des.
No matching records found

Gene-Drug: Aster Plot


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Drug ID
Drug Name
Model Num.
iGMDRD353 PD0325901 1
iGMDRD309 17AAG 2
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Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in SALL2

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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