SERPINB3
Summary:
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| serpin family B member 3 | MIM:600517 | Ensembl:ENSG00000057149 | HGNC:HGNC:10569 | PA35538 | 18q21.33 |
GO terms in SERPINB3
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| CC | TAS | GO:0005576 | extracellular region |
| CC | IBA | GO:0005615 | extracellular space |
| CC | HDA | GO:0005634 | nucleus |
| CC | IDA | GO:0005634 | nucleus |
| CC | IDA | GO:0005737 | cytoplasm |
| CC | IDA | GO:0031410 | cytoplasmic vesicle |
| CC | HDA | GO:0031982 | vesicle |
| CC | TAS | GO:0035578 | azurophil granule lumen |
| CC | HDA | GO:0070062 | extracellular exosome |
| BP | IMP | GO:0008284 | positive regulation of cell proliferation |
| BP | IDA | GO:0010466 | negative regulation of peptidase activity |
| BP | IMP | GO:0010718 | positive regulation of epithelial to mesenchymal transition |
| BP | IDA | GO:0010950 | positive regulation of endopeptidase activity |
| BP | IBA | GO:0010951 | negative regulation of endopeptidase activity |
| BP | IMP | GO:0010951 | negative regulation of endopeptidase activity |
| BP | IMP | GO:0030335 | positive regulation of cell migration |
| BP | IMP | GO:0035425 | autocrine signaling |
| BP | IMP | GO:0038001 | paracrine signaling |
| BP | IDA | GO:0043086 | negative regulation of catalytic activity |
| BP | TAS | GO:0043312 | neutrophil degranulation |
| BP | IMP | GO:0043508 | negative regulation of JUN kinase activity |
| BP | IDA | GO:0045861 | negative regulation of proteolysis |
| BP | IEA | GO:0046718 | viral entry into host cell |
| MF | IDA | GO:0001618 | virus receptor activity |
| MF | IPI | GO:0002020 | protease binding |
| MF | IBA | GO:0004867 | serine-type endopeptidase inhibitor activity |
| MF | NAS | GO:0004867 | serine-type endopeptidase inhibitor activity |
| MF | IMP | GO:0004869 | cysteine-type endopeptidase inhibitor activity |
Gene expression in normal tissue: SERPINB3
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in SERPINB3
| Database | Pathway ID | Pathway Des. |
|---|---|---|
| kegg | hsa05146 | Amoebiasis - Homo sapiens (human) |
| netpath | Pathway_EGFR1 | EGFR1 |
| reactome | R-HSA-168249 | Innate Immune System |
| reactome | R-HSA-168256 | Immune System |
| reactome | R-HSA-6798695 | Neutrophil degranulation |
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in SERPINB3
CLASSFICATION
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