SEC14L1
Summary: The protein encoded by this gene belongs to the SEC14 cytosolic factor family. It has similarity to yeast SEC14 and to Japanese flying squid RALBP which suggests a possible role of the gene product in an intracellular transport system. Multiple alternatively spliced transcript variants have been found for this gene; some variants represent read-through transcripts that include exons from the upstream gene C17orf86. [provided by RefSeq, Feb 2011].
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| SEC14 like lipid binding 1 | MIM:601504 | Ensembl:ENSG00000129657 | HGNC:HGNC:10698 | PA35621 | 17q25.2-q25.3 |
GO terms in SEC14L1
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| CC | IDA | GO:0005654 | nucleoplasm |
| CC | IC | GO:0005737 | cytoplasm |
| CC | IDA | GO:0005737 | cytoplasm |
| CC | IDA | GO:0005794 | Golgi apparatus |
| CC | IDA | GO:0005829 | cytosol |
| BP | IDA | GO:0015871 | choline transport |
| BP | IMP | GO:0039536 | negative regulation of RIG-I signaling pathway |
| BP | IEA | GO:0045087 | innate immune response |
| MF | IPI | GO:0005515 | protein binding |
| MF | IPI | GO:0039552 | RIG-I binding |
| MF | IDA | GO:0098772 | molecular function regulator |
Gene expression in normal tissue: SEC14L1
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in SEC14L1
| Database | Pathway ID | Pathway Des. |
|---|---|---|
| wikipathways | WP2880 | Glucocorticoid Receptor Pathway |
| wikipathways | WP2882 | Nuclear Receptors Meta-Pathway |
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in SEC14L1
CLASSFICATION
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