NEUROG2
Summary: This gene encodes a neural-specific basic helix-loop-helix (bHLH) transcription factor that can specify a neuronal fate on ectodermal cells and is expressed in neural progenitor cells within the developing central and peripheral nervous systems. The protein product of this gene also plays a role in the differentiation and survival of midbrain dopaminergic neurons. [provided by RefSeq, Apr 2012].
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Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
Nameneurogenin 2 OMIM IDMIM:606624 Ensembl IDEnsembl:ENSG00000178403 HGNC IDHGNC:HGNC:13805 PHARMGKB IDPA31570 Map Location4q25 | |||||
GO terms in NEUROG2
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Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| MF | ISA | GO:0000981 | RNA polymerase II transcription factor activity, sequence-specific DNA binding |
| MF | ISM | GO:0000981 | RNA polymerase II transcription factor activity, sequence-specific DNA binding |
| MF | IEA | GO:0046983 | protein dimerization activity |
| MF | ISS | GO:0070888 | E-box binding |
| CC | IEA | GO:0005634 | nucleus |
| BP | IEA | GO:0006351 | transcription, DNA-templated |
Gene expression in normal tissue: NEUROG2
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in NEUROG2
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Database | Pathway ID | Pathway Des. |
|---|---|---|
| wikipathways | WP2855 | Dopaminergic Neurogenesis |
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Gene-Drug: Aster Plot
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Drug ID | Drug Name | Model Num. |
|---|---|---|
| iGMDRD353 | PD0325901 | 2 |
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Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in NEUROG2
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Model | Level | Reference ID | Tissue | Cancer | Drug | Clinical Response | Source | |
|---|---|---|---|---|---|---|---|---|
| No matching records found | ||||||||
CLASSFICATION
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