LRRC4

Summary: This gene is significantly downregulated in primary brain tumors. The exact function of the protein encoded by this gene is unknown. [provided by RefSeq, Jul 2008].

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Name
OMIM ID
Ensembl ID
HGNC ID
PHARMGKB ID
Map Location
Nameleucine rich repeat containing 4
OMIM IDMIM:610486
Ensembl IDEnsembl:ENSG00000128594
HGNC IDHGNC:HGNC:15586
PHARMGKB IDPA30463
Map Location7q32.1

GO terms in LRRC4


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Term Type
Evidence Type
GO Term ID
GO Des.
MF IPI GO:0005515 protein binding
BP IEA GO:0050807 regulation of synapse organization
BP IEA GO:0097119 postsynaptic density protein 95 clustering
CC IEA GO:0016021 integral component of membrane
CC IEA GO:0030054 cell junction
CC IEA GO:0043197 dendritic spine
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Gene expression in normal tissue: LRRC4

Gene-model tissue-cancer distribution: Bubble Plot

undefinetissue: undefine cancer: undefined model num: 0undefinedtissue: undefined cancer: PANCAN model num: 1

Gene-drug pathway distribution

Protein stability and degradation1

Pathways in LRRC4


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Database
Pathway ID
Pathway Des.
kegg hsa04360 Axon guidance - Homo sapiens (human)
kegg hsa04514 Cell adhesion molecules (CAMs) - Homo sapiens (human)
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Gene-Drug: Aster Plot


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Drug ID
Drug Name
Model Num.
iGMDRD309 17AAG 1
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Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in LRRC4

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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