BLVRB

Summary: The final step in heme metabolism in mammals is catalyzed by the cytosolic biliverdin reductase enzymes A and B (EC 1.3.1.24).[supplied by OMIM, Jul 2009].

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Name
OMIM ID
Ensembl ID
HGNC ID
PHARMGKB ID
Map Location
Namebiliverdin reductase B
OMIM IDMIM:600941
Ensembl IDEnsembl:ENSG00000090013
HGNC IDHGNC:HGNC:1063
PHARMGKB IDPA25374
Map Location19q13.2

GO terms in BLVRB


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Term Type
Evidence Type
GO Term ID
GO Des.
CC IDA GO:0005654 nucleoplasm
CC IDA GO:0005829 cytosol
CC TAS GO:0005829 cytosol
CC IDA GO:0005886 plasma membrane
CC IEA GO:0043195 terminal bouton
CC HDA GO:0070062 extracellular exosome
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Gene expression in normal tissue: BLVRB

Gene-model tissue-cancer distribution: Bubble Plot

undefinetissue: undefine cancer: undefined model num: 0undefinedtissue: undefined cancer: PANCAN model num: 1

Gene-drug pathway distribution

Protein stability and degradation1

Pathways in BLVRB


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Database
Pathway ID
Pathway Des.
wikipathways WP2882 Nuclear Receptors Meta-Pathway
wikipathways WP2884 NRF2 pathway
kegg hsa00740 Riboflavin metabolism - Homo sapiens (human)
kegg hsa00860 Porphyrin and chlorophyll metabolism - Homo sapiens (human)
pharmgkb PA165980834 Methylene Blue Pathway, Pharmacodynamics
humancyc PWY-5874 heme degradation
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Gene-Drug: Aster Plot


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Drug ID
Drug Name
Model Num.
iGMDRD309 17AAG 1
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Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in BLVRB

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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