GNPNAT1
Summary:
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| glucosamine-phosphate N-acetyltransferase 1 | MIM:616510 | Ensembl:ENSG00000100522 | HGNC:HGNC:19980 | PA134901326 | 14q22.1 |
GO terms in GNPNAT1
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| MF | IBA | GO:0004343 | glucosamine 6-phosphate N-acetyltransferase activity |
| MF | TAS | GO:0004343 | glucosamine 6-phosphate N-acetyltransferase activity |
| MF | IBA | GO:0008080 | N-acetyltransferase activity |
| MF | IPI | GO:0042802 | identical protein binding |
| MF | IBA | GO:0048029 | monosaccharide binding |
| MF | IEA | GO:0048029 | monosaccharide binding |
| CC | IEA | GO:0000139 | Golgi membrane |
| CC | IEA | GO:0005770 | late endosome |
| CC | IBA | GO:0005783 | endoplasmic reticulum |
| CC | IBA | GO:0005793 | endoplasmic reticulum-Golgi intermediate compartment |
| CC | IEA | GO:0005793 | endoplasmic reticulum-Golgi intermediate compartment |
| CC | IBA | GO:0005794 | Golgi apparatus |
| CC | TAS | GO:0005829 | cytosol |
| CC | IEA | GO:0010008 | endosome membrane |
| BP | IEA | GO:0001889 | liver development |
| BP | IEA | GO:0006041 | glucosamine metabolic process |
| BP | IEA | GO:0006044 | N-acetylglucosamine metabolic process |
| BP | IBA | GO:0006045 | N-acetylglucosamine biosynthetic process |
| BP | IBA | GO:0006048 | UDP-N-acetylglucosamine biosynthetic process |
| BP | IEA | GO:0006048 | UDP-N-acetylglucosamine biosynthetic process |
| BP | TAS | GO:0006048 | UDP-N-acetylglucosamine biosynthetic process |
| BP | IEA | GO:1990830 | cellular response to leukemia inhibitory factor |
Gene expression in normal tissue: GNPNAT1
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in GNPNAT1
| Database | Pathway ID | Pathway Des. |
|---|---|---|
| wikipathways | WP2004 | miR-targeted genes in lymphocytes - TarBase |
| wikipathways | WP2005 | miR-targeted genes in muscle cell - TarBase |
| smpdb | SMP00045 | Amino Sugar Metabolism |
| smpdb | SMP00072 | Glutamate Metabolism |
| smpdb | SMP00136 | 2-Hydroxyglutric Aciduria (D And L Form) |
| smpdb | SMP00216 | Sialuria or French Type Sialuria |
| smpdb | SMP00217 | Sialuria or French Type Sialuria |
| smpdb | SMP00240 | Salla Disease/Infantile Sialic Acid Storage Disease |
| smpdb | SMP00243 | 4-Hydroxybutyric Aciduria/Succinic Semialdehyde Dehydrogenase Deficiency |
| smpdb | SMP00339 | Hyperinsulinism-Hyperammonemia Syndrome |
| smpdb | SMP00385 | Homocarnosinosis |
| smpdb | SMP00390 | Tay-Sachs Disease |
| smpdb | SMP00534 | G(M2)-Gangliosidosis: Variant B, Tay-sachs disease |
| smpdb | SMP00567 | Succinic semialdehyde dehydrogenase deficiency |
| kegg | hsa00520 | Amino sugar and nucleotide sugar metabolism - Homo sapiens (human) |
| humancyc | PWY-5514 | UDP-N-acetyl-D-galactosamine biosynthesis II |
| humancyc | UDPNACETYLGALSYN-PWY | UDP-N-acetyl-D-glucosamine biosynthesis II |
| reactome | R-HSA-392499 | Metabolism of proteins |
| reactome | R-HSA-446193 | Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein |
| reactome | R-HSA-446203 | Asparagine N-linked glycosylation |
| reactome | R-HSA-446210 | Synthesis of UDP-N-acetyl-glucosamine |
| reactome | R-HSA-446219 | Synthesis of substrates in N-glycan biosythesis |
| reactome | R-HSA-597592 | Post-translational protein modification |
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in GNPNAT1
CLASSFICATION
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