SLC1A5
Summary: The SLC1A5 gene encodes a sodium-dependent neutral amino acid transporter that can act as a receptor for RD114/type D retrovirus (Larriba et al., 2001 [PubMed 11781704]).[supplied by OMIM, Jan 2011].
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Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
---|---|---|---|---|---|
OMIM IDMIM:109190 Ensembl IDEnsembl:ENSG00000105281 HGNC IDHGNC:HGNC:10943 PHARMGKB IDPA35830 Map Location19q13.32 |
Gene Categories:
TRANSPORTERGO terms in SLC1A5
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Term Type | Evidence Type | GO Term ID | GO Des. |
---|---|---|---|
MF | IEA | GO:0001618 | virus receptor activity |
MF | IPI | GO:0005515 | protein binding |
MF | TAS | GO:0015171 | amino acid transmembrane transporter activity |
MF | TAS | GO:0015175 | neutral amino acid transmembrane transporter activity |
MF | TAS | GO:0015186 | L-glutamine transmembrane transporter activity |
MF | IEA | GO:0015194 | L-serine transmembrane transporter activity |
Gene expression in normal tissue: SLC1A5
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in SLC1A5
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Database | Pathway ID | Pathway Des. |
---|---|---|
kegg | hsa04974 | Protein digestion and absorption - Homo sapiens (human) |
kegg | hsa05230 | Central carbon metabolism in cancer - Homo sapiens (human) |
smpdb | SMP00001 | Citrullinemia Type I |
smpdb | SMP00002 | Carbamoyl Phosphate Synthetase Deficiency |
smpdb | SMP00003 | Argininosuccinic Aciduria |
smpdb | SMP00059 | Urea Cycle |
Gene-Drug: Aster Plot
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Drug ID | Drug Name | Model Num. |
---|---|---|
iGMDRD998 | Repligen-136 | 1 |
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Gene in drug-gene network: Network Plot

Gene-drug targets distribution
Gene Structure: PDB
Models in SLC1A5
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Model | Level | Reference ID | Tissue | Cancer | Drug | Clinical Response | Source | |
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No matching records found |