SNRPD2
Summary: The protein encoded by this gene belongs to the small nuclear ribonucleoprotein core protein family. It is required for pre-mRNA splicing and small nuclear ribonucleoprotein biogenesis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009].
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| small nuclear ribonucleoprotein D2 polypeptide | MIM:601061 | Ensembl:ENSG00000125743 | HGNC:HGNC:11159 | PA36000 | 19q13.32 |
GO terms in SNRPD2
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| MF | HDA | GO:0003723 | RNA binding |
| MF | IPI | GO:0005515 | protein binding |
| CC | TAS | GO:0005654 | nucleoplasm |
| CC | TAS | GO:0005681 | spliceosomal complex |
| CC | IBA | GO:0005682 | U5 snRNP |
| CC | IBA | GO:0005685 | U1 snRNP |
| CC | IDA | GO:0005685 | U1 snRNP |
| CC | IBA | GO:0005686 | U2 snRNP |
| CC | IDA | GO:0005687 | U4 snRNP |
| CC | IDA | GO:0005689 | U12-type spliceosomal complex |
| CC | IDA | GO:0005829 | cytosol |
| CC | TAS | GO:0005829 | cytosol |
| CC | TAS | GO:0030532 | small nuclear ribonucleoprotein complex |
| CC | IDA | GO:0034709 | methylosome |
| CC | IDA | GO:0034715 | pICln-Sm protein complex |
| CC | IDA | GO:0034719 | SMN-Sm protein complex |
| CC | IBA | GO:0046540 | U4/U6 x U5 tri-snRNP complex |
| CC | HDA | GO:0070062 | extracellular exosome |
| CC | IDA | GO:0071007 | U2-type catalytic step 2 spliceosome |
| CC | IBA | GO:0071013 | catalytic step 2 spliceosome |
| CC | IDA | GO:0071013 | catalytic step 2 spliceosome |
| BP | TAS | GO:0000245 | spliceosomal complex assembly |
| BP | IBA | GO:0000387 | spliceosomal snRNP assembly |
| BP | IDA | GO:0000387 | spliceosomal snRNP assembly |
| BP | TAS | GO:0000387 | spliceosomal snRNP assembly |
| BP | IC | GO:0000398 | mRNA splicing, via spliceosome |
| BP | TAS | GO:0000398 | mRNA splicing, via spliceosome |
| BP | TAS | GO:0008380 | RNA splicing |
| BP | TAS | GO:0051170 | import into nucleus |
Gene expression in normal tissue: SNRPD2
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in SNRPD2
| Database | Pathway ID | Pathway Des. |
|---|---|---|
| wikipathways | WP411 | mRNA Processing |
| netpath | Pathway_EGFR1 | EGFR1 |
| kegg | hsa03040 | Spliceosome - Homo sapiens (human) |
| reactome | R-HSA-191859 | snRNP Assembly |
| reactome | R-HSA-194441 | Metabolism of non-coding RNA |
| reactome | R-HSA-72163 | mRNA Splicing - Major Pathway |
| reactome | R-HSA-72165 | mRNA Splicing - Minor Pathway |
| reactome | R-HSA-72172 | mRNA Splicing |
| reactome | R-HSA-72203 | Processing of Capped Intron-Containing Pre-mRNA |
| reactome | R-HSA-8953854 | Metabolism of RNA |
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in SNRPD2
CLASSFICATION
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