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TNFAIP1

Summary: This gene was identified as a gene whose expression can be induced by the tumor necrosis factor alpha (TNF) in umbilical vein endothelial cells. Studies of a similar gene in mouse suggest that the expression of this gene is developmentally regulated in a tissue-specific manner. [provided by RefSeq, Jul 2008].

Name	OMIM ID	Ensembl ID	HGNC ID	PHARMGKB ID	Map Location
TNF alpha induced protein 1	MIM:191161	Ensembl:ENSG00000109079	HGNC:HGNC:11894	PA36591	17q11.2

GO terms in TNFAIP1

Term Type	Evidence Type	GO Term ID	GO Des.
MF	IDA	GO:0004842	ubiquitin-protein transferase activity
MF	IPI	GO:0005515	protein binding
MF	IDA	GO:0017049	GTP-Rho binding
MF	IEA	GO:0019904	protein domain specific binding
MF	IPI	GO:0042802	identical protein binding
CC	IDA	GO:0005730	nucleolus
CC	IDA	GO:0005737	cytoplasm
CC	IDA	GO:0005768	endosome
CC	IDA	GO:0031463	Cul3-RING ubiquitin ligase complex
BP	ISS	GO:0006260	DNA replication
BP	TAS	GO:0006915	apoptotic process
BP	IEP	GO:0006955	immune response
BP	IMP	GO:0016477	cell migration
BP	IDA	GO:0016567	protein ubiquitination
BP	IEA	GO:0016567	protein ubiquitination
BP	IMP	GO:0035024	negative regulation of Rho protein signal transduction
BP	IMP	GO:0043149	stress fiber assembly
BP	IDA	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
BP	IEA	GO:0045740	positive regulation of DNA replication
BP	IEA	GO:0051260	protein homooligomerization

Gene expression in normal tissue: TNFAIP1

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Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in TNFAIP1

Database	Pathway ID	Pathway Des.

Gene-Drug: Aster Plot

Drug ID	Drug Name	Model Num.
iGMDRD68	Paclitaxel	1

Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in TNFAIP1

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