TNFAIP1
Summary: This gene was identified as a gene whose expression can be induced by the tumor necrosis factor alpha (TNF) in umbilical vein endothelial cells. Studies of a similar gene in mouse suggest that the expression of this gene is developmentally regulated in a tissue-specific manner. [provided by RefSeq, Jul 2008].
Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
---|---|---|---|---|---|
TNF alpha induced protein 1 | MIM:191161 | Ensembl:ENSG00000109079 | HGNC:HGNC:11894 | PA36591 | 17q11.2 |
GO terms in TNFAIP1
Term Type | Evidence Type | GO Term ID | GO Des. |
---|---|---|---|
MF | IDA | GO:0004842 | ubiquitin-protein transferase activity |
MF | IPI | GO:0005515 | protein binding |
MF | IDA | GO:0017049 | GTP-Rho binding |
MF | IEA | GO:0019904 | protein domain specific binding |
MF | IPI | GO:0042802 | identical protein binding |
CC | IDA | GO:0005730 | nucleolus |
CC | IDA | GO:0005737 | cytoplasm |
CC | IDA | GO:0005768 | endosome |
CC | IDA | GO:0031463 | Cul3-RING ubiquitin ligase complex |
BP | ISS | GO:0006260 | DNA replication |
BP | TAS | GO:0006915 | apoptotic process |
BP | IEP | GO:0006955 | immune response |
BP | IMP | GO:0016477 | cell migration |
BP | IDA | GO:0016567 | protein ubiquitination |
BP | IEA | GO:0016567 | protein ubiquitination |
BP | IMP | GO:0035024 | negative regulation of Rho protein signal transduction |
BP | IMP | GO:0043149 | stress fiber assembly |
BP | IDA | GO:0043161 | proteasome-mediated ubiquitin-dependent protein catabolic process |
BP | IEA | GO:0045740 | positive regulation of DNA replication |
BP | IEA | GO:0051260 | protein homooligomerization |
Gene expression in normal tissue: TNFAIP1
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in TNFAIP1
Database | Pathway ID | Pathway Des. |
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Gene in drug-gene network: Network Plot
![](image/gene_network_legends.png)
Gene-drug targets distribution
Gene Structure: PDB
Models in TNFAIP1