UTY
Summary: This gene encodes a protein containing tetratricopeptide repeats which are thought to be involved in protein-protein interactions. The encoded protein is also a minor histocompatibility antigen which may induce graft rejection of male stem cell grafts. A large number of alternatively spliced transcripts have been observed for this gene, but the full length nature of some of these variants has not been determined. [provided by RefSeq, Apr 2012].
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Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
---|---|---|---|---|---|
OMIM IDMIM:400009 Ensembl IDEnsembl:ENSG00000183878 HGNC IDHGNC:HGNC:12638 PHARMGKB IDPA37263 Map LocationYq11.221 |
Gene Categories:
HISTONE MODIFICATIONGO terms in UTY
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Term Type | Evidence Type | GO Term ID | GO Des. |
---|---|---|---|
MF | IBA | GO:0000978 | RNA polymerase II proximal promoter sequence-specific DNA binding |
MF | IBA | GO:0001190 | transcriptional activator activity, RNA polymerase II transcription factor binding |
MF | IBA | GO:0003682 | chromatin binding |
MF | IBA | GO:0031490 | chromatin DNA binding |
MF | TAS | GO:0032452 | histone demethylase activity |
MF | IBA | GO:0043565 | sequence-specific DNA binding |
Gene expression in normal tissue: UTY
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in UTY
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Database | Pathway ID | Pathway Des. |
---|---|---|
kegg | hsa05202 | Transcriptional misregulation in cancer - Homo sapiens (human) |
reactome | R-HSA-3214842 | HDMs demethylate histones |
reactome | R-HSA-3247509 | Chromatin modifying enzymes |
reactome | R-HSA-4839726 | Chromatin organization |
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Gene-Drug: Aster Plot
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Drug ID | Drug Name | Model Num. |
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iGMDRD353 | PD0325901 | 1 |
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Gene in drug-gene network: Network Plot

Gene-drug targets distribution
Gene Structure: PDB
Models in UTY
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Model | Level | Reference ID | Tissue | Cancer | Drug | Clinical Response | Source | |
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No matching records found |