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ZNF43

Summary: This gene belongs to the C2H2-type zinc finger gene family. The zinc finger proteins are involved in gene regulation and development, and are quite conserved throughout evolution. Like this gene product, a third of the zinc finger proteins containing C2H2 fingers also contain the KRAB domain, which has been found to be involved in protein-protein interactions. [provided by RefSeq, Jul 2008].

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Name	OMIM ID	Ensembl ID	HGNC ID	PHARMGKB ID	Map Location
Namezinc finger protein 43 OMIM IDMIM:603972 Ensembl IDEnsembl:ENSG00000198521 HGNC IDHGNC:HGNC:13109 PHARMGKB IDPA37684 Map Location19p12

GO terms in ZNF43

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Term Type	Evidence Type	GO Term ID	GO Des.
MF	ISA	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
MF	NAS	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
MF	IEA	GO:0003677	DNA binding
MF	IEA	GO:0046872	metal ion binding
CC	IEA	GO:0005634	nucleus
BP	IEA	GO:0006351	transcription, DNA-templated

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Gene expression in normal tissue: ZNF43

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Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in ZNF43

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Database	Pathway ID	Pathway Des.
reactome	R-HSA-212436	Generic Transcription Pathway
reactome	R-HSA-73857	RNA Polymerase II Transcription
reactome	R-HSA-74160	Gene expression (Transcription)

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Gene-Drug: Aster Plot

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Drug ID	Drug Name	Model Num.
iGMDRD309	17AAG	2

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Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in ZNF43

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	Model	Level	Reference ID	Tissue	Cancer	Drug	Clinical Response	Source
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