DNALI1
Summary: This gene is the human homolog of the Chlamydomonas inner dynein arm gene, p28. The precise function of this gene is not known, however, it is a potential candidate for immotile cilia syndrome (ICS). Ultrastructural defects of the inner dynein arms are seen in patients with ICS. Immotile mutant strains of Chlamydomonas, a biflagellated algae, exhibit similar defects. [provided by RefSeq, Jul 2008].
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Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
OMIM IDMIM:602135 Ensembl IDEnsembl:ENSG00000163879 HGNC IDHGNC:HGNC:14353 PHARMGKB IDPA38381 Map Location1p34.3 | |||||
GO terms in DNALI1
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Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| CC | IBA | GO:0005737 | cytoplasm |
| CC | IDA | GO:0005737 | cytoplasm |
| CC | IDA | GO:0005929 | cilium |
| CC | IBA | GO:0005930 | axoneme |
| CC | IDA | GO:0005930 | axoneme |
| CC | IBA | GO:0030175 | filopodium |
Gene expression in normal tissue: DNALI1
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in DNALI1
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Database | Pathway ID | Pathway Des. |
|---|---|---|
| kegg | hsa05016 | Huntington,s disease - Homo sapiens (human) |
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Gene-Drug: Aster Plot
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Drug ID | Drug Name | Model Num. |
|---|---|---|
| iGMDRD353 | PD0325901 | 1 |
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Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in DNALI1
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Model | Level | Reference ID | Tissue | Cancer | Drug | Clinical Response | Source | |
|---|---|---|---|---|---|---|---|---|
| No matching records found | ||||||||
CLASSFICATION
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