NABP2
Summary: Single-stranded DNA (ssDNA)-binding proteins, such as OBFC2B, are ubiquitous and essential for a variety of DNA metabolic processes, including replication, recombination, and detection and repair of damage (Richard et al., 2008 [PubMed 18449195]).[supplied by OMIM, Jun 2008].
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| nucleic acid binding protein 2 | MIM:612104 | Ensembl:ENSG00000139579 | HGNC:HGNC:28412 | PA143485567 | 12q13.3 |
GO terms in NABP2
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| CC | IDA | GO:0000784 | nuclear chromosome, telomeric region |
| CC | IDA | GO:0005634 | nucleus |
| CC | IDA | GO:0005654 | nucleoplasm |
| CC | TAS | GO:0005654 | nucleoplasm |
| CC | IDA | GO:0005829 | cytosol |
| CC | IDA | GO:0070876 | SOSS complex |
| BP | IMP | GO:0000724 | double-strand break repair via homologous recombination |
| BP | IMP | GO:0006281 | DNA repair |
| BP | ISS | GO:0006281 | DNA repair |
| BP | IMP | GO:0006974 | cellular response to DNA damage stimulus |
| BP | IMP | GO:0007093 | mitotic cell cycle checkpoint |
| BP | IMP | GO:0010212 | response to ionizing radiation |
| BP | TAS | GO:0042795 | snRNA transcription by RNA polymerase II |
| BP | IMP | GO:0051972 | regulation of telomerase activity |
| BP | IMP | GO:0070200 | establishment of protein localization to telomere |
| BP | IMP | GO:1904355 | positive regulation of telomere capping |
| MF | IDA | GO:0003697 | single-stranded DNA binding |
| MF | IPI | GO:0005515 | protein binding |
| MF | IDA | GO:0061730 | C-rich strand telomeric DNA binding |
| MF | IPI | GO:0070182 | DNA polymerase binding |
| MF | IDA | GO:0098505 | G-rich strand telomeric DNA binding |
Gene expression in normal tissue: NABP2
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in NABP2
| Database | Pathway ID | Pathway Des. |
|---|---|---|
| reactome | R-HSA-6807505 | RNA polymerase II transcribes snRNA genes |
| reactome | R-HSA-6807505 | RNA polymerase II transcribes snRNA genes |
| reactome | R-HSA-73857 | RNA Polymerase II Transcription |
| reactome | R-HSA-73857 | RNA Polymerase II Transcription |
| reactome | R-HSA-74160 | Gene expression (Transcription) |
| reactome | R-HSA-74160 | Gene expression (Transcription) |
| wikipathways | WP2857 | Mesodermal Commitment Pathway |
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in NABP2
CLASSFICATION
Copyright © 2018 Modellab | All Rights Reserved
Disclaimer: iGMDR is intended for research purposes only. Its information cannot be used for emergencies or medical or professional advice.