FBXL15
Summary:
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| F-box and leucine rich repeat protein 15 | MIM:610287 | Ensembl:ENSG00000107872 | HGNC:HGNC:28155 | PA134928704 | 10q24.32 |
GO terms in FBXL15
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| MF | EXP | GO:0004842 | ubiquitin-protein transferase activity |
| MF | IBA | GO:0004842 | ubiquitin-protein transferase activity |
| MF | IDA | GO:0004842 | ubiquitin-protein transferase activity |
| MF | TAS | GO:0004842 | ubiquitin-protein transferase activity |
| MF | IPI | GO:0005515 | protein binding |
| CC | IDA | GO:0005737 | cytoplasm |
| CC | TAS | GO:0005829 | cytosol |
| CC | IBA | GO:0019005 | SCF ubiquitin ligase complex |
| CC | IDA | GO:0019005 | SCF ubiquitin ligase complex |
| BP | IBA | GO:0000086 | G2/M transition of mitotic cell cycle |
| BP | IMP | GO:0000086 | G2/M transition of mitotic cell cycle |
| BP | TAS | GO:0000209 | protein polyubiquitination |
| BP | ISS | GO:0009953 | dorsal/ventral pattern formation |
| BP | IDA | GO:0016567 | protein ubiquitination |
| BP | ISS | GO:0030282 | bone mineralization |
| BP | IBA | GO:0030513 | positive regulation of BMP signaling pathway |
| BP | IMP | GO:0030513 | positive regulation of BMP signaling pathway |
| BP | IBA | GO:0031146 | SCF-dependent proteasomal ubiquitin-dependent protein catabolic process |
| BP | IDA | GO:0031146 | SCF-dependent proteasomal ubiquitin-dependent protein catabolic process |
| BP | TAS | GO:0043687 | post-translational protein modification |
Gene expression in normal tissue: FBXL15
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in FBXL15
| Database | Pathway ID | Pathway Des. |
|---|---|---|
| reactome | R-HSA-1280218 | Adaptive Immune System |
| reactome | R-HSA-168256 | Immune System |
| reactome | R-HSA-392499 | Metabolism of proteins |
| reactome | R-HSA-597592 | Post-translational protein modification |
| reactome | R-HSA-8951664 | Neddylation |
| reactome | R-HSA-983168 | Antigen processing: Ubiquitination & Proteasome degradation |
| reactome | R-HSA-983169 | Class I MHC mediated antigen processing & presentation |
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in FBXL15
CLASSFICATION
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