PARP8


Summary:

NameOMIM IDEnsembl IDHGNC IDPHARMGKB IDMap Location
poly(ADP-ribose) polymerase family member 8Ensembl:ENSG00000151883HGNC:HGNC:26124PA1349032015q11.1

Gene Categories:

DRUGGABLE GENOME

GO terms in PARP8


Term TypeEvidence TypeGO Term IDGO Des.
MFIBAGO:0003950NAD+ ADP-ribosyltransferase activity
MFIEAGO:0003950NAD+ ADP-ribosyltransferase activity
CCIBAGO:0005622intracellular
CCIDAGO:0005622intracellular
BPIBAGO:0006471protein ADP-ribosylation

Gene expression in normal tissue: PARP8

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in PARP8


DatabasePathway IDPathway Des.
reactomeR-HSA-1430728Metabolism
reactomeR-HSA-196807Nicotinate metabolism
reactomeR-HSA-196849Metabolism of water-soluble vitamins and cofactors
reactomeR-HSA-196854Metabolism of vitamins and cofactors
reactomeR-HSA-197264Nicotinamide salvaging
wikipathwaysWP2857Mesodermal Commitment Pathway

Gene-Drug: Aster Plot


Drug IDDrug NameModel Num.
iGMDRD68Paclitaxel1

Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in PARP8

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