TNIP3
Summary:
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| TNFAIP3 interacting protein 3 | MIM:608019 | Ensembl:ENSG00000050730 | HGNC:HGNC:19315 | PA134934429 | 4q27 |
GO terms in TNIP3
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| MF | IPI | GO:0005515 | protein binding |
| MF | IDA | GO:0031593 | polyubiquitin modification-dependent protein binding |
| CC | TAS | GO:0005829 | cytosol |
| BP | IDA | GO:0002756 | MyD88-independent toll-like receptor signaling pathway |
| BP | IEA | GO:0006954 | inflammatory response |
| BP | TAS | GO:0016579 | protein deubiquitination |
| BP | IDA | GO:0034142 | toll-like receptor 4 signaling pathway |
| BP | IDA | GO:0043124 | negative regulation of I-kappaB kinase/NF-kappaB signaling |
| BP | IDA | GO:0071222 | cellular response to lipopolysaccharide |
Gene expression in normal tissue: TNIP3
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in TNIP3
| Database | Pathway ID | Pathway Des. |
|---|---|---|
| reactome | R-HSA-392499 | Metabolism of proteins |
| reactome | R-HSA-5688426 | Deubiquitination |
| reactome | R-HSA-5689896 | Ovarian tumor domain proteases |
| reactome | R-HSA-597592 | Post-translational protein modification |
| wikipathways | WP3303 | Rac1-Pak1-p38-MMP-2 pathway |
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in TNIP3
CLASSFICATION
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