ATAT1
Summary: This gene encodes a protein that localizes to clathrin-coated pits, where it acetylates alpha tubulin on lysine 40. This process may be important in microtubule growth, for instance during chemotaxis and the formation of cilium. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016].
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Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
OMIM IDMIM:615556 Ensembl IDEnsembl:ENSG00000137343 HGNC IDHGNC:HGNC:21186 PHARMGKB IDPA134948212 Map Location6p21.33 | |||||
GO terms in ATAT1
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Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| MF | IDA | GO:0004468 | lysine N-acetyltransferase activity, acting on acetyl phosphate as donor |
| MF | TAS | GO:0004468 | lysine N-acetyltransferase activity, acting on acetyl phosphate as donor |
| MF | IBA | GO:0019799 | tubulin N-acetyltransferase activity |
| MF | IDA | GO:0019799 | tubulin N-acetyltransferase activity |
| MF | IMP | GO:0019799 | tubulin N-acetyltransferase activity |
| MF | IDA | GO:0050662 | coenzyme binding |
Gene expression in normal tissue: ATAT1
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in ATAT1
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Database | Pathway ID | Pathway Des. |
|---|---|---|
| reactome | R-HSA-1852241 | Organelle biogenesis and maintenance |
| reactome | R-HSA-5617833 | Cilium Assembly |
| wikipathways | WP2004 | miR-targeted genes in lymphocytes - TarBase |
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Gene-Drug: Aster Plot
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Drug ID | Drug Name | Model Num. |
|---|---|---|
| iGMDRD353 | PD0325901 | 1 |
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Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in ATAT1
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Model | Level | Reference ID | Tissue | Cancer | Drug | Clinical Response | Source | |
|---|---|---|---|---|---|---|---|---|
| No matching records found | ||||||||
CLASSFICATION
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