CHD9
Summary:
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| chromodomain helicase DNA binding protein 9 | MIM:616936 | Ensembl:ENSG00000177200 | HGNC:HGNC:25701 | PA128394727 | 16q12.2 |
GO terms in CHD9
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| CC | TAS | GO:0005654 | nucleoplasm |
| CC | IEA | GO:0005737 | cytoplasm |
| BP | IEA | GO:0006325 | chromatin organization |
| BP | IEA | GO:0006351 | transcription, DNA-templated |
| BP | IEA | GO:0006355 | regulation of transcription, DNA-templated |
| BP | TAS | GO:0019216 | regulation of lipid metabolic process |
| MF | IEA | GO:0003677 | DNA binding |
| MF | IEA | GO:0004386 | helicase activity |
| MF | IEA | GO:0005524 | ATP binding |
Gene expression in normal tissue: CHD9
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in CHD9
| Database | Pathway ID | Pathway Des. |
|---|---|---|
| reactome | R-HSA-1266738 | Developmental Biology |
| reactome | R-HSA-1368082 | RORA activates gene expression |
| reactome | R-HSA-1368108 | BMAL1:CLOCK,NPAS2 activates circadian gene expression |
| reactome | R-HSA-1430728 | Metabolism |
| reactome | R-HSA-1430728 | Metabolism |
| reactome | R-HSA-1592230 | Mitochondrial biogenesis |
| reactome | R-HSA-1655829 | Regulation of cholesterol biosynthesis by SREBP (SREBF) |
| reactome | R-HSA-1852241 | Organelle biogenesis and maintenance |
| reactome | R-HSA-1989781 | PPARA activates gene expression |
| reactome | R-HSA-1989781 | PPARA activates gene expression |
| reactome | R-HSA-2151201 | Transcriptional activation of mitochondrial biogenesis |
| reactome | R-HSA-2426168 | Activation of gene expression by SREBF (SREBP) |
| reactome | R-HSA-381340 | Transcriptional regulation of white adipocyte differentiation |
| reactome | R-HSA-400206 | Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) |
| reactome | R-HSA-400206 | Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) |
| reactome | R-HSA-400253 | Circadian Clock |
| reactome | R-HSA-400253 | Circadian Clock |
| reactome | R-HSA-556833 | Metabolism of lipids |
| reactome | R-HSA-556833 | Metabolism of lipids |
| reactome | R-HSA-8957322 | Metabolism of steroids |
Gene-Drug: Aster Plot
| Drug ID | Drug Name | Model Num. |
|---|---|---|
| iGMDRD64 | Parbendazole | 5 |
| iGMDRD356 | PNU-74654 | 2 |
| iGMDRD188 | Piperlongumine | 6 |
| iGMDRD74 | Idarubicin | 1 |
| iGMDRD399 | Selumetinib | 4 |
| iGMDRD888 | Compound 44 | 2 |
| iGMDRD224 | Necrostatin-1 | 2 |
| iGMDRD171 | Pemetrexed | 2 |
| iGMDRD801 | 2,4-dideoxy-DC-45-A2 | 3 |
| iGMDRD294 | Batimastat | 2 |
| iGMDRD187 | BRD9876 | 4 |
| iGMDRD52 | Rotenone | 4 |
| iGMDRD247 | Blebbistatin | 3 |
| iGMDRD474 | Avrainvillamide | 2 |
| iGMDRD260 | FQI-2 | 3 |
| iGMDRD466 | Chaetocin | 4 |
| iGMDRD679 | Bistramide A | 2 |
| iGMDRD639 | YK 4-279 | 3 |
| iGMDRD316 | N9-Isopropyl-olomoucine | 1 |
| iGMDRD152 | 179324-69-7 | 1 |
| iGMDRD61 | Kinetin riboside | 2 |
| iGMDRD427 | ABT737 | 3 |
| iGMDRD433 | Lexibulin | 1 |
| iGMDRD151 | CHM-1 | 5 |
| iGMDRD420 | Leucascandrolide A | 6 |
| iGMDRD322 | FK 866 | 3 |
| iGMDRD367 | Ro 28-1675 | 1 |
| iGMDRD662 | JQ-1 | 2 |
| iGMDRD366 | PI-103 | 2 |
| iGMDRD289 | Parthenolide | 3 |
| iGMDRD705 | Nakiterpiosin | 3 |
| iGMDRD105 | Triptolide | 5 |
| iGMDRD213 | SMR000068650 | 6 |
| iGMDRD121 | GMX1778 | 2 |
| iGMDRD202 | Curcumin | 1 |
| iGMDRD5 | Tyrphostin AG 1478 | 2 |
| iGMDRD123 | Isoevodiamine | 3 |
| iGMDRD237 | ABT-751 | 1 |
| iGMDRD79 | Gemcitabine | 5 |
| iGMDRD405 | PIK-75 | 2 |
| iGMDRD330 | BRD4132 | 4 |
| iGMDRD248 | BRD4354 | 2 |
| iGMDRD690 | PRIMA-1MET | 2 |
| iGMDRD60 | Quinoclamine | 4 |
| iGMDRD640 | CAY10618 | 2 |
| iGMDRD268 | Cerulenin | 4 |
| iGMDRD451 | Serdemetan | 2 |
| iGMDRD100 | Zebularine | 4 |
| iGMDRD562 | Navitoclax | 3 |
| iGMDRD885 | Compound 110 | 2 |
| iGMDRD441 | TW 37 | 2 |
| iGMDRD802 | 4-methylfasudil | 4 |
| iGMDRD255 | SB225002 | 2 |
| iGMDRD297 | Austocystin D | 2 |
| iGMDRD280 | CYTOCHALASIN B | 3 |
| iGMDRD359 | OSW-1 | 2 |
| iGMDRD380 | Pifithrin-alpha | 2 |
| iGMDRD446 | LY 2183240 | 2 |
| iGMDRD201 | SKI II | 1 |
| iGMDRD193 | Fqi1 | 3 |
| iGMDRD494 | Neopeltolide | 3 |
| iGMDRD599 | Salermide | 5 |
| iGMDRD579 | PF750 | 3 |
| iGMDRD659 | Avagacestat (BMS-708163) | 1 |
| iGMDRD1008 | SR-II-138A | 1 |
| iGMDRD772 | BRD4770 | 2 |
| iGMDRD246 | NPC26 | 6 |
| iGMDRD695 | FR-180204 | 1 |
| iGMDRD414 | MST-312 | 3 |
| iGMDRD6 | AM-580 | 2 |
| iGMDRD434 | BMS-536924 | 2 |
| iGMDRD481 | Dactolisib | 1 |
| iGMDRD231 | Importazole | 3 |
| iGMDRD267 | Oligomycin A | 2 |
| iGMDRD85 | Ursolic acid | 5 |
| iGMDRD57 | Chloropentafluorobenzene | 3 |
| iGMDRD345 | Compound 10b [PMID: 11504634] | 2 |
| iGMDRD84 | Lovastatin acid | 3 |
| iGMDRD307 | Manumycin A | 2 |
| iGMDRD486 | Tosedostat | 1 |
| iGMDRD512 | nutlin 3 | 4 |
| iGMDRD607 | Ubistatin B | 2 |
| iGMDRD148 | Pifithrin-mu | 1 |
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in CHD9
CLASSFICATION
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