KLHL15


Summary: This gene encodes a member of the kelch-like family of proteins that share a common domain structure consisting of an N-terminal broad-complex, tramtrack, bric-a-brac/poxvirus and zinc finger domain and C-terminal kelch repeat motifs. The encoded protein may be involved in protein ubiquitination and cytoskeletal organization. [provided by RefSeq, Apr 2009].

NameOMIM IDEnsembl IDHGNC IDPHARMGKB IDMap Location
kelch like family member 15MIM:300980Ensembl:ENSG00000174010HGNC:HGNC:29347PA134934728Xp22.11

GO terms in KLHL15


Term TypeEvidence TypeGO Term IDGO Des.
BPIDAGO:0006511ubiquitin-dependent protein catabolic process
BPIEAGO:0016567protein ubiquitination
BPIDAGO:0071630nuclear protein quality control by the ubiquitin-proteasome system
BPIDAGO:2000042negative regulation of double-strand break repair via homologous recombination
CCIDAGO:0005634nucleus
CCIDAGO:0031463Cul3-RING ubiquitin ligase complex
MFIPIGO:0005515protein binding

Gene expression in normal tissue: KLHL15

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in KLHL15


DatabasePathway IDPathway Des.

Gene-Drug: Aster Plot


Drug IDDrug NameModel Num.
iGMDRD353PD03259011

Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in KLHL15

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