KLHL15

Summary: This gene encodes a member of the kelch-like family of proteins that share a common domain structure consisting of an N-terminal broad-complex, tramtrack, bric-a-brac/poxvirus and zinc finger domain and C-terminal kelch repeat motifs. The encoded protein may be involved in protein ubiquitination and cytoskeletal organization. [provided by RefSeq, Apr 2009].

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Name
OMIM ID
Ensembl ID
HGNC ID
PHARMGKB ID
Map Location
Namekelch like family member 15
OMIM IDMIM:300980
Ensembl IDEnsembl:ENSG00000174010
HGNC IDHGNC:HGNC:29347
PHARMGKB IDPA134934728
Map LocationXp22.11

GO terms in KLHL15


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Term Type
Evidence Type
GO Term ID
GO Des.
BP IDA GO:0006511 ubiquitin-dependent protein catabolic process
BP IEA GO:0016567 protein ubiquitination
BP IDA GO:0071630 nuclear protein quality control by the ubiquitin-proteasome system
BP IDA GO:2000042 negative regulation of double-strand break repair via homologous recombination
CC IDA GO:0005634 nucleus
CC IDA GO:0031463 Cul3-RING ubiquitin ligase complex
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Gene expression in normal tissue: KLHL15

Gene-model tissue-cancer distribution: Bubble Plot

undefinetissue: undefine cancer: undefined model num: 0undefinedtissue: undefined cancer: PANCAN model num: 1

Gene-drug pathway distribution

Pathways in KLHL15


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Database
Pathway ID
Pathway Des.
No matching records found

Gene-Drug: Aster Plot


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Drug ID
Drug Name
Model Num.
iGMDRD353 PD0325901 1
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Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in KLHL15

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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