ABTB1
Summary: This gene encodes a protein with an ankyrin repeat region and two BTB/POZ domains, which are thought to be involved in protein-protein interactions. Expression of this gene is activated by the phosphatase and tensin homolog, a tumor suppressor. Alternate splicing results in three transcript variants. [provided by RefSeq, Mar 2010].
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| ankyrin repeat and BTB domain containing 1 | MIM:608308 | Ensembl:ENSG00000114626 | HGNC:HGNC:18275 | PA24418 | 3q21.3 |
GO terms in ABTB1
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| CC | IDA | GO:0005730 | nucleolus |
| CC | IBA | GO:0005737 | cytoplasm |
| CC | IDA | GO:0005829 | cytosol |
| CC | IDA | GO:0005886 | plasma membrane |
| BP | IEA | GO:0006414 | translational elongation |
| BP | IBA | GO:0030162 | regulation of proteolysis |
| BP | IBA | GO:0043161 | proteasome-mediated ubiquitin-dependent protein catabolic process |
| MF | IEA | GO:0003746 | translation elongation factor activity |
| MF | IPI | GO:0005515 | protein binding |
| MF | IBA | GO:0031625 | ubiquitin protein ligase binding |
Gene expression in normal tissue: ABTB1
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in ABTB1
| Database | Pathway ID | Pathway Des. |
|---|
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in ABTB1
CLASSFICATION
Copyright © 2018 Modellab | All Rights Reserved
Disclaimer: iGMDR is intended for research purposes only. Its information cannot be used for emergencies or medical or professional advice.