GDPD5
Summary: Glycerophosphodiester phosphodiesterases (GDPDs; EC 3.1.4.46), such as GDPD5, are involved in glycerol metabolism (Lang et al., 2008 [PubMed 17578682]).[supplied by OMIM, Jan 2010].
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| glycerophosphodiester phosphodiesterase domain containing 5 | MIM:609632 | Ensembl:ENSG00000158555 | HGNC:HGNC:28804 | PA142671743 | 11q13.4-q13.5 |
Gene Categories:
TUMOR SUPPRESSORGO terms in GDPD5
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| CC | IEA | GO:0016021 | integral component of membrane |
| CC | IEA | GO:0030426 | growth cone |
| CC | IEA | GO:0043025 | neuronal cell body |
| CC | IEA | GO:0097038 | perinuclear endoplasmic reticulum |
| BP | IEA | GO:0006629 | lipid metabolic process |
| BP | IEA | GO:0021522 | spinal cord motor neuron differentiation |
| BP | IEA | GO:0021895 | cerebral cortex neuron differentiation |
| BP | IEA | GO:0031175 | neuron projection development |
| BP | IEA | GO:0045666 | positive regulation of neuron differentiation |
| BP | IEA | GO:0045746 | negative regulation of Notch signaling pathway |
| BP | IEA | GO:0045787 | positive regulation of cell cycle |
| BP | IEA | GO:0048505 | regulation of timing of cell differentiation |
| MF | IPI | GO:0005515 | protein binding |
| MF | IEA | GO:0008889 | glycerophosphodiester phosphodiesterase activity |
| MF | IEA | GO:0047389 | glycerophosphocholine phosphodiesterase activity |
Gene expression in normal tissue: GDPD5
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in GDPD5
| Database | Pathway ID | Pathway Des. |
|---|---|---|
| reactome | R-HSA-1430728 | Metabolism |
| reactome | R-HSA-1483255 | PI Metabolism |
| reactome | R-HSA-1483257 | Phospholipid metabolism |
| reactome | R-HSA-556833 | Metabolism of lipids |
| reactome | R-HSA-6814848 | Glycerophospholipid catabolism |
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in GDPD5
CLASSFICATION
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