IMMP2L
Summary: This gene encodes a protein involved in processing the signal peptide sequences used to direct mitochondrial proteins to the mitochondria. The encoded protein resides in the mitochondria and is one of the necessary proteins for the catalytic activity of the mitochondrial inner membrane peptidase (IMP) complex. Two variants that encode the same protein have been described for this gene. [provided by RefSeq, Sep 2011].
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Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
OMIM IDMIM:605977 Ensembl IDEnsembl:ENSG00000184903 HGNC IDHGNC:HGNC:14598 PHARMGKB IDPA134887258 Map Location7q31.1 | |||||
GO terms in IMMP2L
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Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| MF | ISS | GO:0008233 | peptidase activity |
| MF | IEA | GO:0008236 | serine-type peptidase activity |
| BP | IEA | GO:0001541 | ovarian follicle development |
| BP | IBA | GO:0006627 | protein processing involved in protein targeting to mitochondrion |
| BP | ISS | GO:0006627 | protein processing involved in protein targeting to mitochondrion |
| BP | IEA | GO:0006801 | superoxide metabolic process |
Gene expression in normal tissue: IMMP2L
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in IMMP2L
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Database | Pathway ID | Pathway Des. |
|---|---|---|
| kegg | hsa03060 | Protein export - Homo sapiens (human) |
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Gene-Drug: Aster Plot
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Drug ID | Drug Name | Model Num. |
|---|---|---|
| iGMDRD353 | PD0325901 | 1 |
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Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in IMMP2L
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Model | Level | Reference ID | Tissue | Cancer | Drug | Clinical Response | Source | |
|---|---|---|---|---|---|---|---|---|
| No matching records found | ||||||||
CLASSFICATION
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