MND1

Summary: The product of the MND1 gene associates with HOP2 (MIM 608665) to form a stable heterodimeric complex that binds DNA and stimulates the recombinase activity of RAD51 (MIM 179617) and DMC1 (MIM 602721) (Chi et al., 2007 [PubMed 17639080]). Both the MND1 and HOP2 genes are indispensable for meiotic recombination.[supplied by OMIM, Mar 2008].

Loading, please wait...
Name
OMIM ID
Ensembl ID
HGNC ID
PHARMGKB ID
Map Location
Namemeiotic nuclear divisions 1
OMIM IDMIM:611422
Ensembl IDEnsembl:ENSG00000121211
HGNC IDHGNC:HGNC:24839
PHARMGKB IDPA143485544
Map Location4q31.3

Gene Categories:

DNA REPAIR

GO terms in MND1


Loading, please wait...
Term Type
Evidence Type
GO Term ID
GO Des.
BP IBA GO:0007131 reciprocal meiotic recombination
MF IBA GO:0003690 double-stranded DNA binding
Showing 1 to 2 of 2 rows

Gene expression in normal tissue: MND1

Gene-model tissue-cancer distribution: Bubble Plot

undefinetissue: undefine cancer: undefined model num: 0undefinedtissue: undefined cancer: PANCAN model num: 2

Gene-drug pathway distribution

Metabolic pathways1

Pathways in MND1


Loading, please wait...
Database
Pathway ID
Pathway Des.
reactome R-HSA-1474165 Reproduction
reactome R-HSA-1500620 Meiosis
reactome R-HSA-1640170 Cell Cycle
reactome R-HSA-912446 Meiotic recombination
Showing 1 to 4 of 4 rows

Gene-Drug: Aster Plot


Loading, please wait...
Drug ID
Drug Name
Model Num.
iGMDRD68 Paclitaxel 2
Showing 1 to 1 of 1 rows

Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in MND1

Loading, please wait...
Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

​​​​

SITE
DATATYPES
CLASSFICATION
Map

Copyright © 2018 Modellab | All Rights Reserved

Disclaimer: iGMDR is intended for research purposes only. Its information cannot be used for emergencies or medical or professional advice.