ATRN
Summary: This gene encodes both membrane-bound and secreted protein isoforms. A membrane-bound isoform exhibits sequence similarity with the mouse mahogany protein, a receptor involved in controlling obesity. A secreted isoform is involved in the initial immune cell clustering during inflammatory responses that may regulate the chemotactic activity of chemokines. [provided by RefSeq, Apr 2016].
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Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
Nameattractin OMIM IDMIM:603130 Ensembl IDEnsembl:ENSG00000088812 HGNC IDHGNC:HGNC:885 PHARMGKB IDPA25178 Map Location20p13 | |||||
Gene Categories:
DRUGGABLE GENOMEGO terms in ATRN
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Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| BP | IEA | GO:0006954 | inflammatory response |
| BP | IEA | GO:0006979 | response to oxidative stress |
| BP | IEA | GO:0007165 | signal transduction |
| BP | IEA | GO:0021549 | cerebellum development |
| BP | IEA | GO:0040014 | regulation of multicellular organism growth |
| BP | IEA | GO:0042552 | myelination |
Gene expression in normal tissue: ATRN
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in ATRN
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Database | Pathway ID | Pathway Des. |
|---|---|---|
| No matching records found | ||
Gene-Drug: Aster Plot
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Drug ID | Drug Name | Model Num. |
|---|---|---|
| iGMDRD353 | PD0325901 | 1 |
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Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in ATRN
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Model | Level | Reference ID | Tissue | Cancer | Drug | Clinical Response | Source | |
|---|---|---|---|---|---|---|---|---|
| No matching records found | ||||||||
CLASSFICATION
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