ATRN
Summary: This gene encodes both membrane-bound and secreted protein isoforms. A membrane-bound isoform exhibits sequence similarity with the mouse mahogany protein, a receptor involved in controlling obesity. A secreted isoform is involved in the initial immune cell clustering during inflammatory responses that may regulate the chemotactic activity of chemokines. [provided by RefSeq, Apr 2016].
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| attractin | MIM:603130 | Ensembl:ENSG00000088812 | HGNC:HGNC:885 | PA25178 | 20p13 |
Gene Categories:
DRUGGABLE GENOMEGO terms in ATRN
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| BP | IEA | GO:0006954 | inflammatory response |
| BP | IEA | GO:0006979 | response to oxidative stress |
| BP | IEA | GO:0007165 | signal transduction |
| BP | IEA | GO:0021549 | cerebellum development |
| BP | IEA | GO:0040014 | regulation of multicellular organism growth |
| BP | IEA | GO:0042552 | myelination |
| BP | IEA | GO:0043473 | pigmentation |
| CC | IDA | GO:0005615 | extracellular space |
| CC | IEA | GO:0005737 | cytoplasm |
| CC | NAS | GO:0005886 | plasma membrane |
| CC | TAS | GO:0005887 | integral component of plasma membrane |
| CC | HDA | GO:0070062 | extracellular exosome |
| MF | IEA | GO:0030246 | carbohydrate binding |
| MF | IEA | GO:0038023 | signaling receptor activity |
Gene expression in normal tissue: ATRN
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in ATRN
| Database | Pathway ID | Pathway Des. |
|---|
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in ATRN
CLASSFICATION
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