GPAT3
Summary: This gene encodes a member of the lysophosphatidic acid acyltransferase protein family. The encoded protein is an enzyme which catalyzes the conversion of glycerol-3-phosphate to lysophosphatidic acid in the synthesis of triacylglycerol. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jan 2012].
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Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
OMIM IDMIM:610958 Ensembl IDEnsembl:ENSG00000138678 HGNC IDHGNC:HGNC:28157 PHARMGKB IDPA162375888 Map Location4q21.23 | |||||
GO terms in GPAT3
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Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| BP | TAS | GO:0006654 | phosphatidic acid biosynthetic process |
| BP | IEA | GO:0016024 | CDP-diacylglycerol biosynthetic process |
| BP | IDA | GO:0019432 | triglyceride biosynthetic process |
| BP | IEA | GO:0019432 | triglyceride biosynthetic process |
| BP | IDA | GO:0032006 | regulation of TOR signaling |
| CC | IDA | GO:0005783 | endoplasmic reticulum |
Gene expression in normal tissue: GPAT3
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in GPAT3
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Database | Pathway ID | Pathway Des. |
|---|---|---|
| humancyc | PWY-5667 | CDP-diacylglycerol biosynthesis |
| humancyc | TRIGLSYN-PWY | triacylglycerol biosynthesis |
| kegg | hsa00561 | Glycerolipid metabolism - Homo sapiens (human) |
| kegg | hsa00564 | Glycerophospholipid metabolism - Homo sapiens (human) |
| wikipathways | WP2456 | HIF1A and PPARG regulation of glycolysis |
| reactome | R-HSA-1430728 | Metabolism |
Gene-Drug: Aster Plot
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in GPAT3
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Model | Level | Reference ID | Tissue | Cancer | Drug | Clinical Response | Source | |
|---|---|---|---|---|---|---|---|---|
| No matching records found | ||||||||
CLASSFICATION
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