LINGO1
Summary:
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| leucine rich repeat and Ig domain containing 1 | MIM:609791 | Ensembl:ENSG00000169783 | HGNC:HGNC:21205 | PA162394087 | 15q24.3 |
Gene Categories:
DRUGGABLE GENOMEGO terms in LINGO1
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| MF | IBA | GO:0005154 | epidermal growth factor receptor binding |
| MF | IPI | GO:0005515 | protein binding |
| CC | TAS | GO:0005886 | plasma membrane |
| CC | IEA | GO:0016021 | integral component of membrane |
| BP | IBA | GO:0007165 | signal transduction |
| BP | TAS | GO:0050771 | negative regulation of axonogenesis |
Gene expression in normal tissue: LINGO1
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in LINGO1
| Database | Pathway ID | Pathway Des. |
|---|---|---|
| reactome | R-HSA-162582 | Signal Transduction |
| reactome | R-HSA-193634 | Axonal growth inhibition (RHOA activation) |
| reactome | R-HSA-193697 | p75NTR regulates axonogenesis |
| reactome | R-HSA-193704 | p75 NTR receptor-mediated signalling |
| reactome | R-HSA-73887 | Death Receptor Signalling |
| netpath | Pathway_BDNF | BDNF |
| pid | p75ntrpathway | p75(NTR)-mediated signaling |
| wikipathways | WP2380 | Brain-Derived Neurotrophic Factor (BDNF) signaling pathway |
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in LINGO1
CLASSFICATION
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