SCIN
Summary: SCIN is a Ca(2+)-dependent actin-severing and -capping protein (Zunino et al., 2001 [PubMed 11568009]).[supplied by OMIM, May 2010].
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Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
Namescinderin OMIM IDMIM:613416 Ensembl IDEnsembl:ENSG00000006747 HGNC IDHGNC:HGNC:21695 PHARMGKB IDPA134981389 Map Location7p21.3 | |||||
GO terms in SCIN
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Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| MF | ISS | GO:0001786 | phosphatidylserine binding |
| MF | ISS | GO:0003779 | actin binding |
| MF | TAS | GO:0003779 | actin binding |
| MF | ISS | GO:0005509 | calcium ion binding |
| MF | TAS | GO:0005509 | calcium ion binding |
| MF | TAS | GO:0005545 | 1-phosphatidylinositol binding |
Gene expression in normal tissue: SCIN
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in SCIN
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Database | Pathway ID | Pathway Des. |
|---|---|---|
| kegg | hsa04666 | Fc gamma R-mediated phagocytosis - Homo sapiens (human) |
| kegg | hsa04810 | Regulation of actin cytoskeleton - Homo sapiens (human) |
| kegg | hsa05203 | Viral carcinogenesis - Homo sapiens (human) |
| wikipathways | WP474 | Endochondral Ossification |
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Gene-Drug: Aster Plot
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Drug ID | Drug Name | Model Num. |
|---|---|---|
| iGMDRD68 | Paclitaxel | 1 |
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Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in SCIN
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Model | Level | Reference ID | Tissue | Cancer | Drug | Clinical Response | Source | |
|---|---|---|---|---|---|---|---|---|
| No matching records found | ||||||||
CLASSFICATION
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