JRK
Summary: This gene encodes a conserved protein that is similar to DNA-binding proteins, such as major centromere autoantigen B (CENPB). Inactivation of the related gene in mice resulted in epileptic seizures. Childhood Absence Epilepsy (CAE) has been mapped to the same chromosomal location (8q24.3) as this gene. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013].
Loading, please wait...
Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
OMIM IDMIM:603210 Ensembl IDEnsembl:ENSG00000234616 HGNC IDHGNC:HGNC:6199 PHARMGKB IDPA30001 Map Location8q24.3 | |||||
GO terms in JRK
Loading, please wait...
Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| MF | IEA | GO:0003677 | DNA binding |
| MF | IPI | GO:0005515 | protein binding |
| CC | ND | GO:0005575 | cellular_component |
| CC | IEA | GO:0005634 | nucleus |
| BP | IMP | GO:0090263 | positive regulation of canonical Wnt signaling pathway |
Showing 1 to 5 of 5 rows
Gene expression in normal tissue: JRK
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in JRK
Loading, please wait...
Database | Pathway ID | Pathway Des. |
|---|---|---|
| No matching records found | ||
Gene-Drug: Aster Plot
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in JRK
Loading, please wait...
Model | Level | Reference ID | Tissue | Cancer | Drug | Clinical Response | Source | |
|---|---|---|---|---|---|---|---|---|
| No matching records found | ||||||||
CLASSFICATION
Copyright © 2018 Modellab | All Rights Reserved
Disclaimer: iGMDR is intended for research purposes only. Its information cannot be used for emergencies or medical or professional advice.