JRK


Summary: This gene encodes a conserved protein that is similar to DNA-binding proteins, such as major centromere autoantigen B (CENPB). Inactivation of the related gene in mice resulted in epileptic seizures. Childhood Absence Epilepsy (CAE) has been mapped to the same chromosomal location (8q24.3) as this gene. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013].

NameOMIM IDEnsembl IDHGNC IDPHARMGKB IDMap Location
Jrk helix-turn-helix proteinMIM:603210Ensembl:ENSG00000234616HGNC:HGNC:6199PA300018q24.3

GO terms in JRK


Term TypeEvidence TypeGO Term IDGO Des.
MFIEAGO:0003677DNA binding
MFIPIGO:0005515protein binding
CCNDGO:0005575cellular_component
CCIEAGO:0005634nucleus
BPIMPGO:0090263positive regulation of canonical Wnt signaling pathway

Gene expression in normal tissue: JRK

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in JRK


DatabasePathway IDPathway Des.

Gene-Drug: Aster Plot


Drug IDDrug NameModel Num.
iGMDRD353PD03259011
iGMDRD30917AAG1

Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in JRK

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