STX10


Summary: This gene belongs to the syntaxin family and encodes a soluble N-ethylmaleimide sensitive factor attachment protein receptor (SNARE). The encoded protein is involved in docking and fusion events at the Golgi apparatus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2012].

NameOMIM IDEnsembl IDHGNC IDPHARMGKB IDMap Location
syntaxin 10MIM:603765Ensembl:ENSG00000104915HGNC:HGNC:11428PA3622819p13.13

GO terms in STX10


Term TypeEvidence TypeGO Term IDGO Des.
MFIBAGO:0000149SNARE binding
MFIBAGO:0005484SNAP receptor activity
MFIPIGO:0005515protein binding
MFIPIGO:0019905syntaxin binding
CCIDAGO:0005802trans-Golgi network
CCIEAGO:0005829cytosol
CCIBAGO:0008021synaptic vesicle
CCIBAGO:0012505endomembrane system
CCIBAGO:0016021integral component of membrane
CCIBAGO:0030285integral component of synaptic vesicle membrane
CCIBAGO:0031201SNARE complex
CCIDAGO:0031982vesicle
CCTASGO:0032588trans-Golgi network membrane
CCIDAGO:0048471perinuclear region of cytoplasm
BPIBAGO:0006886intracellular protein transport
BPIBAGO:0006906vesicle fusion
BPIMPGO:0032880regulation of protein localization
BPIDAGO:0034498early endosome to Golgi transport
BPIBAGO:0042147retrograde transport, endosome to Golgi
BPIDAGO:0042147retrograde transport, endosome to Golgi
BPIBAGO:0048278vesicle docking

Gene expression in normal tissue: STX10

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in STX10


DatabasePathway IDPathway Des.
kegghsa04130SNARE interactions in vesicular transport - Homo sapiens (human)
pharmgkbPA162355621Nicotine Pathway (Dopaminergic Neuron), Pharmacodynamics
reactomeR-HSA-199991Membrane Trafficking
reactomeR-HSA-5653656Vesicle-mediated transport
reactomeR-HSA-6811440Retrograde transport at the Trans-Golgi-Network
reactomeR-HSA-6811442Intra-Golgi and retrograde Golgi-to-ER traffic

Gene-Drug: Aster Plot


Drug IDDrug NameModel Num.
iGMDRD68Paclitaxel2

Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in STX10

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