STX10
Summary: This gene belongs to the syntaxin family and encodes a soluble N-ethylmaleimide sensitive factor attachment protein receptor (SNARE). The encoded protein is involved in docking and fusion events at the Golgi apparatus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2012].
Loading, please wait...
Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
Namesyntaxin 10 OMIM IDMIM:603765 Ensembl IDEnsembl:ENSG00000104915 HGNC IDHGNC:HGNC:11428 PHARMGKB IDPA36228 Map Location19p13.13 | |||||
GO terms in STX10
Loading, please wait...
Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| MF | IBA | GO:0000149 | SNARE binding |
| MF | IBA | GO:0005484 | SNAP receptor activity |
| MF | IPI | GO:0005515 | protein binding |
| MF | IPI | GO:0019905 | syntaxin binding |
| CC | IDA | GO:0005802 | trans-Golgi network |
| CC | IEA | GO:0005829 | cytosol |
Gene expression in normal tissue: STX10
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in STX10
Loading, please wait...
Database | Pathway ID | Pathway Des. |
|---|---|---|
| kegg | hsa04130 | SNARE interactions in vesicular transport - Homo sapiens (human) |
| pharmgkb | PA162355621 | Nicotine Pathway (Dopaminergic Neuron), Pharmacodynamics |
| reactome | R-HSA-199991 | Membrane Trafficking |
| reactome | R-HSA-5653656 | Vesicle-mediated transport |
| reactome | R-HSA-6811440 | Retrograde transport at the Trans-Golgi-Network |
| reactome | R-HSA-6811442 | Intra-Golgi and retrograde Golgi-to-ER traffic |
Showing 1 to 6 of 6 rows
Gene-Drug: Aster Plot
Loading, please wait...
Drug ID | Drug Name | Model Num. |
|---|---|---|
| iGMDRD68 | Paclitaxel | 2 |
Showing 1 to 1 of 1 rows
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in STX10
Loading, please wait...
Model | Level | Reference ID | Tissue | Cancer | Drug | Clinical Response | Source | |
|---|---|---|---|---|---|---|---|---|
| No matching records found | ||||||||
CLASSFICATION
Copyright © 2018 Modellab | All Rights Reserved
Disclaimer: iGMDR is intended for research purposes only. Its information cannot be used for emergencies or medical or professional advice.