BSN
Summary: Neurotransmitters are released from a specific site in the axon terminal called the active zone, which is composed of synaptic vesicles and a meshwork of cytoskeleton underlying the plasma membrane. The protein encoded by this gene is thought to be a scaffolding protein involved in organizing the presynaptic cytoskeleton. The gene is expressed primarily in neurons in the brain. A similar gene product in rodents is concentrated in the active zone of axon terminals and tightly associated with cytoskeletal structures, and is essential for regulating neurotransmitter release from a subset of synapses. [provided by RefSeq, Jul 2008].
Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
OMIM IDMIM:604020 Ensembl IDEnsembl:ENSG00000164061 HGNC IDHGNC:HGNC:1117 PHARMGKB IDPA25434 Map Location3p21.31 | |||||
Gene Categories:
CELL SURFACEGO terms in BSN
Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| MF | IEA | GO:0046872 | metal ion binding |
| BP | TAS | GO:0007268 | chemical synaptic transmission |
| BP | IEA | GO:0007416 | synapse assembly |
| BP | IEA | GO:0035418 | protein localization to synapse |
| BP | IEA | GO:0099526 | presynapse to nucleus signaling pathway |
| CC | TAS | GO:0005634 | nucleus |
Gene expression in normal tissue: BSN
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in BSN
Database | Pathway ID | Pathway Des. |
|---|---|---|
| No matching records found | ||
Gene-Drug: Aster Plot
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in BSN
Model | Level | Reference ID | Tissue | Cancer | Drug | Clinical Response | Source | |
|---|---|---|---|---|---|---|---|---|
| No matching records found | ||||||||
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